Volk et al., 1998 - Google Patents
A BMP responsive transcriptional region in the chicken type X collagen geneVolk et al., 1998
View PDF- Document ID
- 11209205156676162322
- Author
- Volk S
- Luvalle P
- Leask T
- Leboy P
- Publication year
- Publication venue
- Journal of Bone and Mineral Research
External Links
Snippet
Bone morphogenetic proteins (BMPs) were originally identified by their ability to induce ectopic bone formation and have been shown to promote both chondrogenesis and chondrocyte hypertrophy. BMPs have recently been found to activate a membrane …
- 102000028959 Collagen Type X 0 title abstract description 46
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues ; Not used, see subgroups
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Volk et al. | A BMP responsive transcriptional region in the chicken type X collagen gene | |
Xie et al. | Trans‐activation of the mouse cartilage‐derived retinoic acid‐sensitive protein gene by Sox9 | |
Funato et al. | Common regulation of growth arrest and differentiation of osteoblasts by helix-loop-helix factors | |
Kusanagi et al. | Characterization of a bone morphogenetic protein-responsive Smad-binding element | |
Newberry et al. | Reciprocal regulation of osteocalcin transcription by the homeodomain proteins Msx2 and Dlx5 | |
Tsumaki et al. | Bone morphogenetic protein signals are required for cartilage formation and differently regulate joint development during skeletogenesis | |
Lefebvre et al. | A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene | |
Conlon et al. | Inhibition of Xbra transcription activation causes defects in mesodermal patterning and reveals autoregulation of Xbra in dorsal mesoderm | |
Cserjesi et al. | Scleraxis: a basic helix-loop-helix protein that prefigures skeletal formation during mouse embryogenesis | |
Im et al. | Inhibitory effects of insulin-like growth factor-1 and osteogenic protein-1 on fibronectin fragment-and interleukin-1β-stimulated matrix metalloproteinase-13 expression in human chondrocytes | |
Zehentner et al. | The transcription factor Sox9 is involved in BMP‐2 signaling | |
Gerstenfeld et al. | Chondrocytes provide morphogenic signals that selectively induce osteogenic differentiation of mesenchymal stem cells | |
Yoshimura et al. | Colocalization of noggin and bone morphogenetic protein‐4 during fracture healing | |
Chatzopoulou et al. | Transcriptional and metabolic effects of glucocorticoid receptor α and β signaling in zebrafish | |
Tadic et al. | Overexpression of Dlx5 in chicken calvarial cells accelerates osteoblastic differentiation | |
Nakayama et al. | Receptor tyrosine kinases inhibit bone morphogenetic protein‐Smad responsive promoter activity and differentiation of murine MC3T3‐E1 osteoblast‐like cells | |
Tavella et al. | Targeted expression of SHH affects chondrocyte differentiation, growth plate organization, and Sox9 expression | |
Uusitalo et al. | Accelerated up‐regulation of L‐Sox5, Sox6, and Sox9 by BMP‐2 gene transfer during murine fracture healing | |
Goodnough et al. | Twist1 mediates repression of chondrogenesis by β-catenin to promote cranial bone progenitor specification | |
Latinkić et al. | Promoter function of the angiogenic inducer Cyr61 gene in transgenic mice: tissue specificity, inducibility during wound healing, and role of the serum response element | |
Lecomte et al. | A new role for sterol regulatory element binding protein 1 transcription factors in the regulation of muscle mass and muscle cell differentiation | |
Bridgewater et al. | Adjacent DNA sequences modulate Sox9 transcriptional activation at paired Sox sites in three chondrocyte‐specific enhancer elements | |
Kontrogianni-Konstantopoulos et al. | Obscurin regulates the organization of myosin into A bands | |
Kan et al. | SOX11 contributes to the regulation of GDF5 in joint maintenance | |
Zheng et al. | Dysregulation of chondrogenesis in human cleidocranial dysplasia |