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Wang et al., 2003 - Google Patents

In vivo measurement of brain metabolites using two‐dimensional double‐quantum MR spectroscopy—exploration of GABA levels in a ketogenic diet

Wang et al., 2003

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Document ID
11278000325604584164
Author
Wang Z
Bergqvist C
Hunter J
Jin D
Wang D
Wehrli S
Zimmerman R
Publication year
Publication venue
Magnetic Resonance in Medicine: An Official Journal of the International Society for Magnetic Resonance in Medicine

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Snippet

A localized proton 2D double‐quantum (DQ) spin‐echo spectroscopy technique was implemented on 1.5 T clinical MRI scanners for the detection of γ‐aminobutyrate (GABA) in the brain. The 2D approach facilitates separation of peaks overlapping with GABA in 1D DQ …
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    • G01R33/5615—Echo train techniques involving acquiring plural, differently encoded, echo signals after one RF excitation, e.g. using gradient refocusing in echo planar imaging [EPI], RF refocusing in rapid acquisition with relaxation enhancement [RARE] or using both RF and gradient refocusing in gradient and spin echo imaging [GRASE]
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    • G01R33/5601—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution involving use of a contrast agent for contrast manipulation, e.g. a paramagnetic, super-paramagnetic, ferromagnetic or hyperpolarised contrast agent
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    • G01R33/485—NMR imaging systems with selection of signals or spectra from particular regions of the volume, e.g. in vivo spectroscopy based on chemical shift information CSI or spectroscopic imaging, e.g. to acquire the spatial distributions of metabolites
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