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Geiersbach et al., 2011 - Google Patents

FOXL2 mutation and large-scale genomic imbalances in adult granulosa cell tumors of the ovary

Geiersbach et al., 2011

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Document ID
1110072189757648552
Author
Geiersbach K
Jarboe E
Jahromi M
Baker C
Paxton C
Tripp S
Schiffman J
Publication year
Publication venue
Cancer genetics

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Adult granulosa cell tumors (AGCTs) are a rare class of ovarian tumors with recurrent cytogenetic abnormalities including trisomy 12, trisomy 14, monosomy 16/deletion 16q, and monosomy 22. Over 90% contain a missense point mutation (C134W) in the FOXL2 gene at …
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