Golledge et al., 2011 - Google Patents
The role of tenascin C in cardiovascular diseaseGolledge et al., 2011
View HTML- Document ID
- 10908774288440981448
- Author
- Golledge J
- Clancy P
- Maguire J
- Lincz L
- Koblar S
- Publication year
- Publication venue
- Cardiovascular research
External Links
Snippet
The extracellular matrix protein tenascin C (TnC) is expressed in a variety of embryonic tissues, but its expression in adult arteries is co-incident with sites of vascular disease. TnC expression has been linked to the development and complications of intimal hyperplasia …
- 108010008125 Tenascin 0 title abstract description 587
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Golledge et al. | The role of tenascin C in cardiovascular disease | |
Osmanagic-Myers et al. | Endothelial progerin expression causes cardiovascular pathology through an impaired mechanoresponse | |
Brisset et al. | Intimal smooth muscle cells of porcine and human coronary artery express S100A4, a marker of the rhomboid phenotype in vitro | |
Wallner et al. | Tenascin-C is expressed in macrophage-rich human coronary atherosclerotic plaque | |
Inamoto et al. | TGFBR2 mutations alter smooth muscle cell phenotype and predispose to thoracic aortic aneurysms and dissections | |
Tsai et al. | TGF-β through Smad3 signaling stimulates vascular smooth muscle cell proliferation and neointimal formation | |
Zachary et al. | Signaling transduction mechanisms mediating biological actions of the vascular endothelial growth factor family | |
Maurage et al. | Endocan expression and localization in human glioblastomas | |
Sugano et al. | Granulocyte colony-stimulating factor attenuates early ventricular expansion after experimental myocardial infarction | |
Italiano Jr et al. | Angiogenesis is regulated by a novel mechanism: pro-and antiangiogenic proteins are organized into separate platelet α granules and differentially released | |
Bujak et al. | The role of TGF-β signaling in myocardial infarction and cardiac remodeling | |
Kudo et al. | Venous identity is lost but arterial identity is not gained during vein graft adaptation | |
Okamoto et al. | Matricellular proteins: new molecular targets to prevent heart failure | |
Merrilees et al. | Retrovirally mediated overexpression of versican v3 by arterial smooth muscle cells induces tropoelastin synthesis and elastic fiber formation in vitro and in neointima after vascular injury | |
Masoud et al. | Apelin directs endothelial cell differentiation and vascular repair following immune-mediated injury | |
Krishna et al. | The role of thrombospondin-1 in cardiovascular health and pathology | |
Hahn et al. | The role of cellular adaptation to mechanical forces in atherosclerosis | |
Chen et al. | Cathepsin S-mediated fibroblast trans-differentiation contributes to left ventricular remodelling after myocardial infarction | |
Herum et al. | Syndecan‐4 protects the heart from the profibrotic effects of thrombin‐cleaved osteopontin | |
Sartore et al. | Myosin gene expression and cell phenotypes in vascular smooth muscle during development, in experimental models, and in vascular disease | |
Morrison et al. | Chemokine-coupled β2 integrin–induced macrophage Rac2–Myosin IIA interaction regulates VEGF-A mRNA stability and arteriogenesis | |
Liu et al. | CCN4 regulates vascular smooth muscle cell migration and proliferation | |
Di Benedetto et al. | Endothelial-to-mesenchymal transition in systemic sclerosis | |
Otsuka et al. | Transforming growth factor beta 1 induces neointima formation through plasminogen activator inhibitor-1–dependent pathways | |
Myers et al. | Alterations of arterial physiology in osteopontin-null mice |