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Sitaraman, 2010 - Google Patents

Sequence specific inhibition of adenoviral replication by the AAV Rep78 ORF

Sitaraman, 2010

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Document ID
10980739235568626010
Author
Sitaraman V
Publication year

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Abstract Hybrid Adenovirus/Adeno-associated viruses (Ad/AAV) combine the capacity, tropism and ease of production of Ad with AAV's ability for site-specific integration (SSI) into chromosome 19 AAVS1. The AAV Rep78 protein is required for SSI although it displays an …
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    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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