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Zhang et al., 2020 - Google Patents

Construction of a tumor microenvironment pH-responsive cleavable PEGylated hyaluronic acid nano-drug delivery system for colorectal cancer treatment

Zhang et al., 2020

Document ID
10805251425003331207
Author
Zhang X
Zhao M
Cao N
Qin W
Zhao M
Wu J
Lin D
Publication year
Publication venue
Biomaterials science

External Links

Snippet

In order to improve active tumor targeting, tumor cell uptake efficiency and circulation time of doxorubicin (DOX) in vivo, we constructed a cleavable PEGylated hyaluronic acid nano-drug delivery system (HA–mPEG2k–DOX) based on a tumor microenvironment pH-responsive …
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    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
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    • A61K9/513—Organic macromolecular compounds; Dendrimers
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