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Pugliese et al., 2019 - Google Patents

Investigation of the CK2-mediated MUS81 phosphorylation and analysis of its relevance for chemosensitivity in BRCA2-deficient human cells

Pugliese et al., 2019

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Document ID
10704540434229482955
Author
Pugliese G
et al.
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The to be carefully regulated to avoid unscheduled targeting structure-specific endonuclease MUS81/EME1 plays important roles in the resolution of recombination intermediates, however, its function needs intermediates during DNA replication, which may …
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
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    • C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
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