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Kwon-Chung et al., 1986 - Google Patents

Encapsulation and melanin formation as indicators of virulence in Cryptococcus neoformans

Kwon-Chung et al., 1986

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Document ID
10602269724957496648
Author
Kwon-Chung K
Rhodes J
Publication year
Publication venue
Infection and immunity

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Acapsular (Cap-) mutants of Cryptococcus neoformans var. neoformans that produce melanin (Mel+) on diphenol media at 30 degrees C but not at 37 degrees C were found to be avirulent for mice. Compared with wild-type isolates, the mutants had a lower rate of L-3 …
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