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Prochnow et al., 2020 - Google Patents

Labyrinthopeptins exert broad-spectrum antiviral activity through lipid-binding-mediated virolysis

Prochnow et al., 2020

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Document ID
10571329330950696791
Author
Prochnow H
Rox K
Birudukota N
Weichert L
Hotop S
Klahn P
Mohr K
Franz S
Banda D
Blockus S
Schreiber J
Haid S
Oeyen M
Martinez J
Süssmuth R
Wink J
Meyerhans A
Goffinet C
Messerle M
Schulz T
Kröger A
Schols D
Pietschmann T
Brönstrup M
Publication year
Publication venue
Journal of Virology

External Links

Snippet

To counteract the serious health threat posed by known and novel viral pathogens, drugs that target a variety of viruses through a common mechanism have attracted recent attention due to their potential in treating (re) emerging infections, for which direct-acting antivirals are …
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof

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Prochnow et al. Labyrinthopeptins exert broad-spectrum antiviral activity through lipid-binding-mediated virolysis
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