Nothing Special   »   [go: up one dir, main page]

Hierlemann et al., 2010 - Google Patents

Growing cells atop microelectronic chips: interfacing electrogenic cells in vitro with CMOS-based microelectrode arrays

Hierlemann et al., 2010

Document ID
10167417242986848521
Author
Hierlemann A
Frey U
Hafizovic S
Heer F
Publication year
Publication venue
Proceedings of the IEEE

External Links

Snippet

Complementary semiconductor-metal-oxide (CMOS) technology is a very powerful technology that can be more or less directly interfaced to electrogenic cells, like heart or brain cells in vitro. To this end, the cells are cultured directly atop the CMOS chips, which …
Continue reading at ieeexplore.ieee.org (other versions)

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/403—Cells and electrode assemblies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/4833—Physical analysis of biological material of solid biological material, e.g. tissue samples, cell cultures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes

Similar Documents

Publication Publication Date Title
Hierlemann et al. Growing cells atop microelectronic chips: interfacing electrogenic cells in vitro with CMOS-based microelectrode arrays
Jones et al. The potential of microelectrode arrays and microelectronics for biomedical research and diagnostics
Obien et al. Revealing neuronal function through microelectrode array recordings
Heer et al. CMOS microelectrode array for the monitoring of electrogenic cells
Heer et al. CMOS microelectrode array for bidirectional interaction with neuronal networks
Lopez et al. A multimodal CMOS MEA for high-throughput intracellular action potential measurements and impedance spectroscopy in drug-screening applications
Ronchi et al. Single-cell electrical stimulation using CMOS-based high-density microelectrode arrays
Morin et al. Investigating neuronal activity with planar microelectrode arrays: achievements and new perspectives
Berdondini et al. High-density electrode array for imaging in vitro electrophysiological activity
Park et al. 1024-pixel CMOS multimodality joint cellular sensor/stimulator array for real-time holistic cellular characterization and cell-based drug screening
US7632674B2 (en) Apparatus for stimulating an animal cell and recording its physiological signal and production and use methods thereof
WO2001033207A1 (en) Microscopic multi-site sensor array with integrated control and analysis circuitry
Fejtl et al. On micro-electrode array revival: its development, sophistication of recording, and stimulation
Lunelli et al. Prototyping a memristive-based device to analyze neuronal excitability
Buitenweg et al. Extracellular detection of active membrane currents in the neuron–electrode interface
Obien et al. Large-Scale, high-resolution microelectrode arrays for interrogation of neurons and networks
Obien et al. CMOS-based high-density microelectrode arrays: technology and applications
WO2004046707A1 (en) Microscopic multi-site sensor array with integrated control and analysis circuitry
Heer et al. Integrated microelectrode arrays
Heer CMOS-based microelectrode array for communication with electrogenic cells
Nam State-of-the-art Technology on MEAs for interfacing live neurons
Masi et al. Multielectrode array: A new approach to plant electrophysiology
Whittington et al. A multi-parameter, feedback-based electrical stimulation system for cardiomyocyte cultures
Qin CMOS Interface for Mammalian Electrogenic Cell Interrogation
Heer et al. Using microelectronics technology to communicate with living cells