Yu et al., 2024 - Google Patents
Vascularized organoid-on-a-chip: design, imaging, and analysisYu et al., 2024
- Document ID
- 10038320065449163707
- Author
- Yu T
- Yang Q
- Peng B
- Gu Z
- Zhu D
- Publication year
- Publication venue
- Angiogenesis
External Links
Snippet
Vascularized organoid-on-a-chip (VOoC) models achieve substance exchange in deep layers of organoids and provide a more physiologically relevant system in vitro. Common designs for VOoC primarily involve two categories: self-assembly of endothelial cells (ECs) …
- 238000004458 analytical method 0 title abstract description 58
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5082—Supracellular entities, e.g. tissue, organisms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
- C12M47/04—Cell isolation or sorting
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Electro-optical investigation, e.g. flow cytometers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M21/00—Bioreactors or fermenters specially adapted for specific uses
- C12M21/08—Bioreactors or fermenters specially adapted for specific uses for producing artificial tissue or for ex-vivo cultivation of tissue
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
- C12M25/14—Scaffolds; Matrices
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/34—Internal compartments or partitions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues ; Not used, see subgroups
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Han et al. | Challenges of applying multicellular tumor spheroids in preclinical phase | |
Saorin et al. | Microfluidic organoids-on-a-chip: The future of human models | |
Radhakrishnan et al. | Organotypic cancer tissue models for drug screening: 3D constructs, bioprinting and microfluidic chips | |
Amirifar et al. | Brain-on-a-chip: Recent advances in design and techniques for microfluidic models of the brain in health and disease | |
Kunze et al. | Micropatterning neural cell cultures in 3D with a multi-layered scaffold | |
US11725173B2 (en) | Highly efficient organoid culture device and system | |
KR101401199B1 (en) | Device and Method of Generating In Vitro Blood Vessels | |
Yu et al. | Vascularized organoid-on-a-chip: design, imaging, and analysis | |
CN104774747B (en) | Microfluidic droplet chip apparatus for cell migration assay experiment and method | |
CN108823145B (en) | In-vitro construction method for simulating blood brain barrier by human brain microvascular formation | |
Han et al. | Imaging technologies for microfluidic biochips | |
Virumbrales-Muñoz et al. | From microfluidics to microphysiological systems: Past, present, and future | |
Ko et al. | Microfluidic high-throughput 3D cell culture | |
Zeng et al. | Patient-derived organoids of lung cancer based on organoids-on-a-chip: enhancing clinical and translational applications | |
Puleo et al. | Applications of MEMS technologies in tissue engineering | |
Li et al. | On-chip modeling of tumor evolution: Advances, challenges and opportunities | |
Schot et al. | Scalable fabrication, compartmentalization and applications of living microtissues | |
Ryoo et al. | Advances in high throughput cell culture technologies for therapeutic screening and biological discovery applications | |
US20230203417A1 (en) | Microfluidic device | |
CN115595266A (en) | Biochip and method for manufacturing the same | |
KR20240029728A (en) | Micro-organic spheres for use in personalized medicine and drug development | |
Hachey et al. | Establishing a physiologic human vascularized micro-tumor model for cancer research | |
CN116478819B (en) | Microfluidic system for constructing three-dimensional organ microenvironment model, and preparation method and application thereof | |
CN113717850A (en) | Non-alcoholic fatty liver in-vitro model building method based on three-dimensional liver-like chip | |
Caballero et al. | Trends in biomaterials for three-dimensional cancer modeling |