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Natarajan et al., 2024 - Google Patents

Acute and chronic glutamate NMDA antagonist treatment attenuates dopamine D1 antagonist-induced reduction of nicotine self-administration in female rats

Natarajan et al., 2024

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Document ID
9908598908854689351
Author
Natarajan S
Abass G
Kim L
Wells C
Rezvani A
Levin E
Publication year
Publication venue
Pharmacology Biochemistry and Behavior

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Multiple interacting neural systems are involved in sustaining nicotine reinforcement. We and others have shown that dopamine D 1 receptors and glutamate NMDA receptors both play important roles in nicotine reinforcement. Blockade of D 1 receptors with the antagonist …
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    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
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