Hervent et al., 2012 - Google Patents
Molecular mechanisms of cardiotoxicity induced by ErbB receptor inhibitor cancer therapeuticsHervent et al., 2012
View HTML- Document ID
- 9826480346145196365
- Author
- Hervent A
- De Keulenaer G
- Publication year
- Publication venue
- International journal of molecular sciences
External Links
Snippet
The introduction of the so-called “targeted therapies”, particularly those drugs that inhibit the activity of tyrosine kinases, has represented a remarkable progress in the treatment of cancer. Although these drugs improve survival rates in cancer, significant cardiotoxicity …
- 201000011510 cancer 0 title abstract description 74
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Hervent et al. | Molecular mechanisms of cardiotoxicity induced by ErbB receptor inhibitor cancer therapeutics | |
Nami et al. | Mechanisms underlying the action and synergism of trastuzumab and pertuzumab in targeting HER2-positive breast cancer | |
Maadi et al. | Trastuzumab mechanism of action; 20 years of research to unravel a dilemma | |
Maennling et al. | Molecular targeting therapy against EGFR family in breast cancer: progress and future potentials | |
Collins et al. | Preclinical characteristics of the irreversible pan-HER kinase inhibitor neratinib compared with lapatinib: implications for the treatment of HER2-positive and HER2-mutated breast cancer | |
Lv et al. | Molecular mechanisms and translational therapies for human epidermal receptor 2 positive breast cancer | |
Nahta et al. | Mechanisms of disease: understanding resistance to HER2-targeted therapy in human breast cancer | |
Garrett et al. | Resistance to HER2-directed antibodies and tyrosine kinase inhibitors: mechanisms and clinical implications | |
Ramakrishnan et al. | Nimotuzumab, a promising therapeutic monoclonal for treatment of tumors of epithelial origin | |
Carrasco-García et al. | Role of receptor tyrosine kinases and their ligands in glioblastoma | |
Agus et al. | Phase I clinical study of pertuzumab, a novel HER dimerization inhibitor, in patients with advanced cancer | |
Markovic et al. | Current role of EGF receptor monoclonal antibodies and tyrosine kinase inhibitors in the management of head and neck squamous cell carcinoma | |
Okines et al. | Trastuzumab: a novel standard option for patients with HER-2-positive advanced gastric or gastro-oesophageal junction cancer | |
Nami et al. | The effects of pertuzumab and its combination with trastuzumab on HER2 homodimerization and phosphorylation | |
Mastro et al. | Trastuzumab as first-line therapy in HER2-positive metastatic breast cancer patients | |
Zhang et al. | Recent progress and advances in HGF/MET-targeted therapeutic agents for cancer treatment | |
Arias-Pinilla et al. | Therapeutic application of monoclonal antibodies in pancreatic cancer: advances, challenges and future opportunities | |
Mukai et al. | Patritumab plus trastuzumab and paclitaxel in human epidermal growth factor receptor 2‐overexpressing metastatic breast cancer | |
Hafeez et al. | New insights into ErbB3 function and therapeutic targeting in cancer | |
Overholser et al. | Anti-tumor effects of peptide therapeutic and peptide vaccine antibody co-targeting HER-1 and HER-2 in esophageal cancer (EC) and HER-1 and IGF-1R in triple-negative breast cancer (TNBC) | |
Shu et al. | A novel anti-HER2 antibody GB235 reverses Trastuzumab resistance in HER2-expressing tumor cells in vitro and in vivo | |
Gameiro et al. | HER2-targeted immunotherapy and combined protocols showed promising antiproliferative effects in Feline mammary carcinoma cell-based models | |
Vathiotis et al. | HER2 aberrations in non-small cell lung cancer: From pathophysiology to targeted therapy | |
Majumder | HER3: toward the prognostic significance, therapeutic potential, current challenges, and future therapeutics in different types of cancer | |
Rubin et al. | Molecular targeting of the human epidermal growth factor receptor-2 (HER2) genes across various cancers |