Zydney, 2021 - Google Patents
New developments in membranes for bioprocessing–A reviewZydney, 2021
- Document ID
- 9549903923332149087
- Author
- Zydney A
- Publication year
- Publication venue
- Journal of Membrane Science
External Links
Snippet
Membrane systems play an essential role in the production of all biopharmaceuticals. This includes initial clarification of cell culture fluid by both depth filtration and tangential flow filtration, biomolecule purification by membrane adsorbers, sterilizing grade filtration and …
- 239000012528 membrane 0 title abstract description 206
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis, ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
- B01D61/142—Ultrafiltration; Microfiltration comprising multiple ultrafiltration or microfiltration steps
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis, ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
- B01D61/145—Ultrafiltration
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2315/00—Details relating to the membrane module operation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Zydney | New developments in membranes for bioprocessing–A review | |
| van Reis et al. | Bioprocess membrane technology | |
| Kalyanpur | Downstream processing in the biotechnology industry | |
| US20210309956A1 (en) | Apparatus for Cell Cultivation | |
| Van Reis et al. | Membrane separations in biotechnology | |
| Rathore et al. | Recent developments in membrane-based separations in biotechnology processes | |
| RU2610667C2 (en) | Method of purification of proteins | |
| Saxena et al. | Membrane-based techniques for the separation and purification of proteins: An overview | |
| KR102027596B1 (en) | Continuous processing methods for biological products | |
| JP6605504B2 (en) | Ultrafiltration unit for continuous exchange of buffers or media from protein solutions | |
| US10494421B2 (en) | System, apparatus and method for biomolecules production | |
| Arunkumar et al. | Investigation of single-pass tangential flow filtration (SPTFF) as an inline concentration step for cell culture harvest | |
| TWI767930B (en) | Methods of processing a fluid including a recombinant therapeutic protein and use thereof | |
| PT2550971T (en) | Devices and methods for integrated continuous manufacturing of biological molecules | |
| JP7568638B2 (en) | Continuous production of recombinant proteins | |
| US10987629B2 (en) | Method for removing biopolymer aggregates and viruses from a fluid | |
| Zydney | Membrane technology for purification of therapeutic proteins | |
| JP2018525219A (en) | Recirculation loop in CFF / TFF disposable channels | |
| WO2015118149A1 (en) | System, apparatus and method for anti-rsv antibodies and formulations | |
| Nejatishahidein et al. | Depth filtration in bioprocessing—new opportunities for an old technology | |
| CN114829371A (en) | Enhanced virus filtration using diafiltration buffer | |
| CN105579572B (en) | Method for purifying high density granular cell culture cutting | |
| Basile et al. | Current Trends and Future Developments on (Bio-) Membranes: Membrane Processes in the Pharmaceutical and Biotechnological Field | |
| US20240140989A1 (en) | A method and system for integrated and continuous viral filtration, concentration and buffer exchange | |
| US20220333060A1 (en) | Process for Purifying Target Substances |