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Barbieri et al., 2001 - Google Patents

Bioreduction of aromatic ketones: preparation of chiral benzyl alcohols in both enantiomeric forms

Barbieri et al., 2001

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Document ID
9388383836691755299
Author
Barbieri C
Bossi L
D'Arrigo P
Fantoni G
Servi S
Publication year
Publication venue
Journal of Molecular Catalysis B: Enzymatic

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Substituted phenacyl chlorides are reduced with whole-cell biocatalysts to give (R)-or (S)- chlorohydrines in high yields and to make them good for high enantiomeric excess. Yields and enantiomeric purity of the S-enantiomer could be increased by performing bioreduction …
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    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C12P7/26—Ketones
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    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
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