Nothing Special   »   [go: up one dir, main page]

Chia, 2017 - Google Patents

Alternative Illumination Beam Geometries in Fluorescence Microscopy for Clinical Prostate Pathology

Chia, 2017

View PDF
Document ID
932315955232011903
Author
Chia J
Publication year

External Links

Snippet

Light sheet microscopy, with the technique developed nearly a century ago and the first application toward fluorescence microscopy of biological specimens occurring in the late twentieth century, has seen a resurgence for applications requiring rapid or 3D imaging of …
Continue reading at repository.arizona.edu (PDF) (other versions)

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G01N21/6458—Fluorescence microscopy
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS, OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052—Optical details of the image generation
    • G02B21/0076—Optical details of the image generation arrangements using fluorescence or luminescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G01N2021/653—Coherent methods [CARS]
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS, OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/06—Means for illuminating specimens
    • G02B21/08—Condensers
    • G02B21/10—Condensers affording dark-field illumination
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS, OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
    • G02B21/365—Control or image processing arrangements for digital or video microscopes
    • G02B21/367—Control or image processing arrangements for digital or video microscopes providing an output produced by processing a plurality of individual source images, e.g. image tiling, montage, composite images, depth sectioning, image comparison
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS, OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/16—Microscopes adapted for ultra-violet illumination; Fluorescence microscopes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/4795—Scattering, i.e. diffuse reflection spatially resolved investigating of object in scattering medium
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS, OR APPARATUS
    • G02B27/00—Other optical systems; Other optical apparatus

Similar Documents

Publication Publication Date Title
US11921042B2 (en) Optical measuring device and process
Micó et al. Resolution enhancement in quantitative phase microscopy
US6909105B1 (en) Method and device for representing an object
Bewersdorf et al. Comparison of I5M and 4Pi‐microscopy
Xu et al. Imaging objects through scattering layers and around corners by retrieval of the scattered point spread function
Siegel et al. High-magnification super-resolution FINCH microscopy using birefringent crystal lens interferometers
Verpillat et al. Dark-field digital holographic microscopy for 3D-tracking of gold nanoparticles
Chowdhury et al. Structured illumination quantitative phase microscopy for enhanced resolution amplitude and phase imaging
Rosen et al. Roadmap on chaos-inspired imaging technologies (CI2-Tech)
Finkeldey et al. Depth-filtering in common-path digital holographic microscopy
Lin et al. One-shot synthetic aperture digital holographic microscopy with non-coplanar angular-multiplexing and coherence gating
Mirecki et al. Low-intensity illumination for lensless digital holographic microscopy with minimized sample interaction
Picazo-Bueno et al. Single-shot, dual-mode, water-immersion microscopy platform for biological applications
Tao et al. Shack-Hartmann wavefront sensing using interferometric focusing of light onto guide-stars
Farah et al. Synthetic spatial aperture holographic third harmonic generation microscopy
Moon et al. Second-harmonic generation microscopy with synthetic aperture and computational adaptive optics
CN109060761B (en) High-speed Raman spectrum scanning imaging method and device with three-dimensional high spatial resolution
Frantz et al. High contrast, isotropic, and uniform 3D-imaging of centimeter-scale scattering samples using structured illumination light-sheet microscopy with axial sweeping
Chia Alternative Illumination Beam Geometries in Fluorescence Microscopy for Clinical Prostate Pathology
Wang et al. 3D-scanning microscopy with adaptive lenses and prisms for zebrafish studies
Haeberlé et al. Improving the lateral resolution in confocal fluorescence microscopy using laterally interfering excitation beams
Lv et al. Reduction of blurring in broadband volume holographic imaging using a deconvolution method
Lin et al. Structured illumination microscopy with direct wavefront sensing
Haouat et al. Visualizing the fine structure and dynamics of living cells with temporal polychromatic digital holographic microscopy
Takesue Transmission-type high-resolution laser scanning microscope