Vaisocherova et al., 2008 - Google Patents
Ultralow fouling and functionalizable surface chemistry based on a zwitterionic polymer enabling sensitive and specific protein detection in undiluted blood plasmaVaisocherova et al., 2008
View HTML- Document ID
- 8792900972278710669
- Author
- Vaisocherova H
- Yang W
- Zhang Z
- Cao Z
- Cheng G
- Piliarik M
- Homola J
- Jiang S
- Publication year
- Publication venue
- Analytical chemistry
External Links
Snippet
A crucial step in the development of implanted medical devices, in vivo diagnostics, and microarrays is the effective prevention of nonspecific protein adsorption from real-world complex media such as blood plasma or serum. In this work, a zwitterionic poly …
- 210000002381 Plasma 0 title abstract description 124
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay
- G01N33/543—Immunoassay; Biospecific binding assay with an insoluble carrier for immobilising immunochemicals
- G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay
- G01N33/543—Immunoassay; Biospecific binding assay with an insoluble carrier for immobilising immunochemicals
- G01N33/54353—Immunoassay; Biospecific binding assay with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay
- G01N33/543—Immunoassay; Biospecific binding assay with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Vaisocherova et al. | Ultralow fouling and functionalizable surface chemistry based on a zwitterionic polymer enabling sensitive and specific protein detection in undiluted blood plasma | |
| Yang et al. | Pursuing “zero” protein adsorption of poly (carboxybetaine) from undiluted blood serum and plasma | |
| Huang et al. | Zwitterionic polymer-based platform with two-layer architecture for ultra low fouling and high protein loading | |
| Baggerman et al. | Romantic surfaces: a systematic overview of stable, biospecific, and antifouling zwitterionic surfaces | |
| Emilsson et al. | Strongly stretched protein resistant poly (ethylene glycol) brushes prepared by grafting-to | |
| Yang et al. | Film thickness dependence of protein adsorption from blood serum and plasma onto poly (sulfobetaine)-grafted surfaces | |
| Rodriguez Emmenegger et al. | Interaction of blood plasma with antifouling surfaces | |
| Ladd et al. | Zwitterionic polymers exhibiting high resistance to nonspecific protein adsorption from human serum and plasma | |
| Lee et al. | Functionalization of poly (oligo (ethylene glycol) methacrylate) films on gold and Si/SiO2 for immobilization of proteins and cells: SPR and QCM studies | |
| Luk et al. | Self-assembled monolayers of alkanethiolates presenting mannitol groups are inert to protein adsorption and cell attachment | |
| Chen et al. | Synthesis and characterization of antifouling poly (N-acryloylaminoethoxyethanol) with ultralow protein adsorption and cell attachment | |
| Andruzzi et al. | Oligo (ethylene glycol) containing polymer brushes as bioselective surfaces | |
| Zhang et al. | Dual-functional biomimetic materials: nonfouling poly (carboxybetaine) with active functional groups for protein immobilization | |
| Rodriguez-Emmenegger et al. | Substrate-independent approach for the generation of functional protein resistant surfaces | |
| Dehghani et al. | Fabrication and interfacial properties of polymer brush gradients by surface-initiated Cu (0)-mediated controlled radical polymerization | |
| Pasche et al. | Poly (l-lysine)-g raft-poly (ethylene glycol) assembled monolayers on niobium oxide surfaces: A quantitative study of the influence of polymer interfacial architecture on resistance to protein adsorption by ToF-SIMS and in situ OWLS | |
| Vaisocherová-Lísalová et al. | Copolymer brush-based ultralow-fouling biorecognition surface platform for food safety | |
| Liu et al. | Grafting hyaluronic acid onto gold surface to achieve low protein fouling in surface plasmon resonance biosensors | |
| Liu et al. | Amino acid-based zwitterionic poly (serine methacrylate) as an antifouling material | |
| Yang et al. | Protein interactions with poly (ethylene glycol) self-assembled monolayers on glass substrates: diffusion and adsorption | |
| Nolan et al. | Phase transition behavior, protein adsorption, and cell adhesion resistance of poly (ethylene glycol) cross-linked microgel particles | |
| Li et al. | Block copolymer modified surfaces for conjugation of biomacromolecules with control of quantity and activity | |
| Bolduc et al. | Monolayers of 3-mercaptopropyl-amino acid to reduce the nonspecific adsorption of serum proteins on the surface of biosensors | |
| Akkahat et al. | Development of a novel antifouling platform for biosensing probe immobilization from methacryloyloxyethyl phosphorylcholine-containing copolymer brushes | |
| Gao et al. | Chain conformation of a new class of PEG-based thermoresponsive polymer brushes grafted on silicon as determined by neutron reflectometry |