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Wang et al., 2019 - Google Patents

Primed acquisition and microhomology-mediated end-joining cooperate to confer specific CRISPR immunity against invasive genetic elements

Wang et al., 2019

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Document ID
8660516226425787128
Author
Wang X
Wu B
Zhang Z
Liu T
Li Y
Hu G
He M
Peng N
Publication year
Publication venue
bioRxiv

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Snippet

CRISPR-Cas systems provide archaea and bacteria with adaptive immunity against invasive genetic elements through acquisition of invader-derived spacers. De novo spacer acquisition generally adapts spacers from both invaders and hosts with a bias towards …
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    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
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