Giacomini et al., 2006 - Google Patents
Infection of human dendritic cells with a Mycobacterium tuberculosis sigE mutant stimulates production of high levels of interleukin-10 but low levels of CXCL10 …Giacomini et al., 2006
View PDF- Document ID
- 8604298020699433770
- Author
- Giacomini E
- Sotolongo A
- Iona E
- Severa M
- Remoli M
- Gafa V
- Lande R
- Fattorini L
- Smith I
- Manganelli R
- Coccia E
- Publication year
- Publication venue
- Infection and immunity
External Links
Snippet
The Mycobacterium tuberculosis genome encodes 13 sigma factors. We have previously shown that mutations in some of these transcriptional activators render M. tuberculosis sensitive to various environmental stresses and can attenuate the virulence phenotype. In …
- 210000004443 Dendritic Cells 0 title abstract description 142
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5047—Cells of the immune system
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay
- G01N33/569—Immunoassay; Biospecific binding assay for micro-organisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
- G01N33/5695—Mycobacteria
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues ; Not used, see subgroups
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
Similar Documents
Publication | Publication Date | Title |
---|---|---|
de Candia et al. | T cells: warriors of SARS-CoV-2 infection | |
Blomgran et al. | Mycobacterium tuberculosis inhibits neutrophil apoptosis, leading to delayed activation of naive CD4 T cells | |
Abdullah et al. | RIG‐I detects infection with live Listeria by sensing secreted bacterial nucleic acids | |
Blomgran et al. | Lung neutrophils facilitate activation of naive antigen-specific CD4+ T cells during Mycobacterium tuberculosis infection | |
Rojas et al. | Regulation of human CD4+ αβ T-cell-receptor-positive (TCR+) and γδ TCR+ T-cell responses to Mycobacterium tuberculosis by interleukin-10 and transforming growth factor β | |
Rao Muvva et al. | Polarization of human monocyte-derived cells with vitamin D promotes control of Mycobacterium tuberculosis infection | |
Phillips et al. | LAG3 expression in active Mycobacterium tuberculosis infections | |
Gafa et al. | Human dendritic cells following Aspergillus fumigatus infection express the CCR7 receptor and a differential pattern of interleukin-12 (IL-12), IL-23, and IL-27 cytokines, which lead to a Th1 response | |
Singh et al. | Re-engineered BCG overexpressing cyclic di-AMP augments trained immunity and exhibits improved efficacy against bladder cancer | |
Loures et al. | MyD88 signaling is required for efficient innate and adaptive immune responses to Paracoccidioides brasiliensis infection | |
Xin et al. | Role of interleukin-1β in activating the CD11chigh CD45RB− dendritic cell subset and priming Leishmania amazonensis-specific CD4+ T cells in vitro and in vivo | |
Hashimoto et al. | Mycobacterium leprae infection in monocyte-derived dendritic cells and its influence on antigen-presenting function | |
Biswas et al. | Negative regulation of Toll‐like receptor signaling plays an essential role in homeostasis of the intestine | |
Pooran et al. | IL-4 subverts mycobacterial containment in Mycobacterium tuberculosis-infected human macrophages | |
Gagliardi et al. | Mycobacterium bovis Bacillus Calmette-Guérin infects DC-SIGN–dendritic cell and causes the inhibition of IL-12 and the enhancement of IL-10 production | |
Duthie et al. | During Trypanosoma cruzi infection CD1d-restricted NK T cells limit parasitemia and augment the antibody response to a glycophosphoinositol-modified surface protein | |
Derbigny et al. | Identifying a role for Toll-like receptor 3 in the innate immune response to Chlamydia muridarum infection in murine oviduct epithelial cells | |
Marr et al. | Cryptococcus neoformans directly stimulates perforin production and rearms NK cells for enhanced anticryptococcal microbicidal activity | |
Giacomini et al. | Infection of human dendritic cells with a Mycobacterium tuberculosis sigE mutant stimulates production of high levels of interleukin-10 but low levels of CXCL10: impact on the T-cell response | |
Kapina et al. | CD27low CD4 T lymphocytes that accumulate in the mouse lungs during mycobacterial infection differentiate from CD27high precursors in situ, produce IFN-γ, and protect the host against tuberculosis infection | |
Kumar et al. | Role of MAIT cells in the immunopathogenesis of inflammatory diseases: new players in old game | |
Siemińska et al. | Mild and asymptomatic COVID-19 convalescents present long-term endotype of immunosuppression associated with neutrophil subsets possessing regulatory functions | |
Giacomini et al. | IFN-β improves BCG immunogenicity by acting on DC maturation | |
Caramori et al. | Immune response to Mycobacterium tuberculosis infection in the parietal pleura of patients with tuberculous pleurisy | |
Fiorentini et al. | HIV-1 matrix protein p17 induces human plasmacytoid dendritic cells to acquire a migratory immature cell phenotype |