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Kozhemyakin et al., 2013 - Google Patents

Somatostatin type-2 receptor activation inhibits glutamate release and prevents status epilepticus

Kozhemyakin et al., 2013

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Document ID
8449366022265334440
Author
Kozhemyakin M
Rajasekaran K
Todorovic M
Kowalski S
Balint C
Kapur J
Publication year
Publication venue
Neurobiology of disease

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Newer therapies are needed for the treatment of status epilepticus (SE) refractory to benzodiazepines. Enhanced glutamatergic neurotransmission leads to SE, and AMPA receptors are modified during SE. Reducing glutamate release during SE is a potential …
Continue reading at www.ncbi.nlm.nih.gov (HTML) (other versions)

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    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
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