Ohishi et al., 2012 - Google Patents
A novel population of cells expressing both hematopoietic and mesenchymal markers is present in the normal adult bone marrow and is augmented in a murine model …Ohishi et al., 2012
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- 8445152960129982068
- Author
- Ohishi M
- Ono W
- Ono N
- Khatri R
- Marzia M
- Baker E
- Root S
- Wilson T
- Iwamoto Y
- Kronenberg H
- Aguila H
- Purton L
- Schipani E
- Publication year
- Publication venue
- The American journal of pathology
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Snippet
Bone marrow (BM) fibrosis is a feature of severe hyperparathyroidism. Consistent with this observation, mice expressing constitutively active parathyroid hormone (PTH)/PTH-related peptide receptors (PPR) in osteoblasts (PPR* Tg) display BM fibrosis. To obtain insight into …
- 210000001185 Bone Marrow 0 title abstract description 88
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues ; Not used, see subgroups
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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