Nothing Special   »   [go: up one dir, main page]

Tsai et al., 2003 - Google Patents

Cyanovirin-N gel as a topical microbicide prevents rectal transmission of SHIV89. 6P in macaques

Tsai et al., 2003

Document ID
7596159047401349850
Author
Tsai C
Emau P
Jiang Y
Tian B
Morton W
Gustafson K
Boyd M
Publication year
Publication venue
AIDS research and human retroviruses

External Links

Snippet

Cyanovirin-N (CV-N), an 11-kDa cyanobacterial protein, potently inactivates diverse strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV) and also prevents virus-to-cell fusion, virus entry, and infection of cells in vitro. These properties make CV-N an attractive …
Continue reading at www.liebertpub.com (other versions)

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/162—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/21—Retroviridae, e.g. equine infectious anemia virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution

Similar Documents

Publication Publication Date Title
Tsai et al. Cyanovirin-N gel as a topical microbicide prevents rectal transmission of SHIV89. 6P in macaques
Jiang et al. SPL7013 gel as a topical microbicide for prevention of vaginal transmission of SHIV89. 6P in macaques
MILMAN et al. Mechanisms of HIV/SIV mucosal transmission
Anderson et al. Targeting Trojan Horse leukocytes for HIV prevention
EP0439513B1 (en) Composition for inhibiting transmission of aids
Greenhead et al. Parameters of human immunodeficiency virus infection of human cervical tissue and inhibition by vaginal virucides
Novembre et al. Development of AIDS in a chimpanzee infected with human immunodeficiency virus type 1
Ferir et al. Synergistic activity profile of griffithsin in combination with tenofovir, maraviroc and enfuvirtide against HIV-1 clade C
Milush et al. Rapid dissemination of SIV following oral inoculation
Jaworski et al. Neutralizing polyclonal IgG present during acute infection prevents rapid disease onset in simian-human immunodeficiency virus SHIVSF162P3-infected infant rhesus macaques
Jennings et al. The inhibitory effect of supermicidal agents on replication of HSV-2 and HIV-1 in-vitro
Caron et al. Protective properties of non-nucleoside reverse transcriptase inhibitor (MC1220) incorporated into liposome against intravaginal challenge of Rhesus macaques with RT-SHIV
Gupta Microbicides: a new hope for HIV prevention
Qiu et al. Poly (4-styrenesulfonic acid-co-maleic acid) is an entry inhibitor against both HIV-1 and HSV infections–Potential as a dual functional microbicide
Garvey et al. Response to Mallet et al.,‘Nodular regenerative hyperplasia is a new cause of chronic liver disease in HIV-infected patients’
Boadi et al. Cellulose acetate 1, 2-benzenedicarboxylate protects against challenge with pathogenic X4 and R5 simian/human immunodeficiency virus
Fraietta et al. Phosphorothioate 2′ deoxyribose oligomers as microbicides that inhibit human immunodeficiency virus type 1 (HIV-1) infection and block Toll-like receptor 7 (TLR7) and TLR9 triggering by HIV-1
Jiang et al. RT-SHIV, an infectious CCR5-tropic chimeric virus suitable for evaluating HIV reverse transcriptase inhibitors in macaque models
Tévi-Bénissan et al. Protection of cynomolgus macaque against cervicovaginal transmission of SIV mac251 by the spermicide benzalkonium chloride
Miller Host and viral factors influencing heterosexual HIV transmission
Herz et al. Viral dynamics of early HIV infection in neonatal macaques after oral exposure to HIV‐2287: an animal model with implications for maternal–neonatal HIV transmission
Pala et al. An African perspective on mucosal immunity and HIV-1
Singh et al. human immunodeficiency virus (HIV) infection
Ramezani et al. Frequency of hepatitis G virus infection among HIV positive subjects with parenteral and sexual exposure
Hung et al. Increase in B19 viral load prior to relapse of anaemia in an AIDS patient with persistent B19 infection