Nothing Special   »   [go: up one dir, main page]

Dagher et al., 2022 - Google Patents

Optogenetic stimulation of midbrain dopamine neurons produces striatal serotonin release

Dagher et al., 2022

View HTML
Document ID
7253265790950556383
Author
Dagher M
Perrotta K
Erwin S
Hachisuka A
Iyer R
Masmanidis S
Yang H
Andrews A
Publication year
Publication venue
ACS chemical neuroscience

External Links

Snippet

Targeting neurons with light-driven opsins is widely used to investigate cell-specific responses. We transfected midbrain dopamine neurons with the excitatory opsin Chrimson. Extracellular basal and stimulated neurotransmitter levels in the dorsal striatum were …
Continue reading at www.ncbi.nlm.nih.gov (HTML) (other versions)

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5082Supracellular entities, e.g. tissue, organisms
    • G01N33/5088Supracellular entities, e.g. tissue, organisms of vertebrates
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic, hydroximic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof

Similar Documents

Publication Publication Date Title
Davoudian et al. Shared and distinct brain regions targeted for immediate early gene expression by ketamine and psilocybin
Pascoli et al. Contrasting forms of cocaine-evoked plasticity control components of relapse
Ellis-Davies Neurobiology with caged calcium
Olson Biochemical mechanisms underlying psychedelic-induced neuroplasticity
Mameli et al. Cocaine-evoked synaptic plasticity: persistence in the VTA triggers adaptations in the NAc
Cachope et al. Selective activation of cholinergic interneurons enhances accumbal phasic dopamine release: setting the tone for reward processing
Marissal et al. Restoring wild-type-like CA1 network dynamics and behavior during adulthood in a mouse model of schizophrenia
Daberkow et al. Amphetamine paradoxically augments exocytotic dopamine release and phasic dopamine signals
Han et al. A subpopulation of nociceptors specifically linked to itch
Saghatelyan et al. Activity-dependent adjustments of the inhibitory network in the olfactory bulb following early postnatal deprivation
Jennings et al. Visualizing hypothalamic network dynamics for appetitive and consummatory behaviors
Chauvette et al. Sleep oscillations in the thalamocortical system induce long-term neuronal plasticity
Parekh et al. Circadian mechanisms underlying reward-related neurophysiology and synaptic plasticity
Grannan et al. Prefrontal cortex-mediated impairments in a genetic model of NMDA receptor hypofunction are reversed by the novel M1 PAM VU6004256
Dagher et al. Optogenetic stimulation of midbrain dopamine neurons produces striatal serotonin release
Aourz et al. Identification of GSK-3 as a potential therapeutic entry point for epilepsy
Siciliano et al. Adaptations of presynaptic dopamine terminals induced by psychostimulant self-administration
Turecek et al. Neuronal regulation of fast synaptotagmin isoforms controls the relative contributions of synchronous and asynchronous release
Ly et al. Activation of 5-HT6 Receptors Modulates Sleep–Wake Activity and Hippocampal Theta Oscillation
Shah et al. Serotonin and glutamate interactions in preclinical schizophrenia models
Yang et al. Sex-and SERT-mediated differences in stimulated serotonin revealed by fast microdialysis
Thal et al. Single quantum dot imaging reveals PKCβ-dependent alterations in membrane diffusion and clustering of an attention-deficit hyperactivity disorder/autism/bipolar disorder-associated dopamine transporter variant
Harris et al. Synaptic plasticity in the bed nucleus of the stria terminalis: underlying mechanisms and potential ramifications for reinstatement of drug-and alcohol-seeking behaviors
Hidalgo et al. Characterization of a novel Drosophila SERT mutant: insights on the contribution of the serotonin neural system to behaviors
Gomez-A et al. Diazepam inhibits electrically evoked and tonic dopamine release in the nucleus accumbens and reverses the effect of amphetamine