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Ruivo et al., 2019 - Google Patents

Improved stability of a novel fluorine-18 labeled TCO analogue for pretargeted PET imaging

Ruivo et al., 2019

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Document ID
7146816292999166009
Author
Ruivo E
Adhikari K
Elvas F
Fissers J
Vangestel C
Staelens S
Stroobants S
Van der Veken P
Wyffels L
Augustyns K
Publication year
Publication venue
Nuclear medicine and biology

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Introduction Biorthogonal pretargeted imaging using the inverse electron demand Diels Alder (IEDDA) reaction between tetrazine (Tz) and trans-cyclooctene (TCO) is one of the most attractive strategies in molecular imaging. It allows the use of short-lived radioisotopes …
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    • A61K51/0453—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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