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Skinner et al., 1993 - Google Patents

Phospholipid transfer activity is relevant to but not sufficient for the essential function of the yeast SEC14 gene product.

Skinner et al., 1993

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Document ID
7060739149798821125
Author
Skinner H
Alb Jr J
Whitters E
Helmkamp Jr G
Bankaitis V
Publication year
Publication venue
The EMBO journal

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To investigate several key aspects of phosphatidylinositol transfer protein (PI‐TP) function in eukaryotic cells, rat PI‐TP was expressed in yeast strains carrying lesions in SEC14, the structural gene for yeast PI‐TP (SEC14p), whose activity is essential for Golgi secretory …
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0006Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
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    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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