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Caira et al., 2003 - Google Patents

Structural characterization, physicochemical properties, and thermal stability of three crystal forms of nifedipine

Caira et al., 2003

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Document ID
7046962773217065176
Author
Caira M
Robbertse Y
Bergh J
Song M
De Villiers M
Publication year
Publication venue
Journal of pharmaceutical sciences

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In this study the single‐crystal X‐ray structure of the solvated species (nifedipine) 2· 1, 4‐ dioxane is reported for the first time. Included solvent molecules are located in isolated cavities in the crystal, yielding a very stable solvate. Desolvation of this species involves …
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