Hammond et al., 2005 - Google Patents
Mitochondrial Glycerol-3-Phosphate Acyltransferase-1 Is Essential inLiver for the Metabolism of ExcessAcyl-CoAsHammond et al., 2005
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- 6837536163534925959
- Author
- Hammond L
- Neschen S
- Romanelli A
- Cline G
- Ilkayeva O
- Shulman G
- Muoio D
- Coleman R
- Publication year
- Publication venue
- Journal of Biological Chemistry
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Snippet
In vitro studies suggest that the mitochondrialglycerol-3-phosphate acyltransferase-1 (mtGPAT1) isoform catalyzes the initialand rate-controlling step in glycerolipid synthesis and aids in partitioningacyl-CoAs toward triacylglycerol synthesis and away from degradative …
- 230000002438 mitochondrial 0 title abstract description 16
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
- C12N9/0083—Miscellaneous (1.14.99)
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