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Helseth et al., 1990 - Google Patents

Changes in the transmembrane region of the human immunodeficiency virus type 1 gp41 envelope glycoprotein affect membrane fusion

Helseth et al., 1990

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Document ID
6580094077502637888
Author
Helseth E
Olshevsky U
Gabuzda D
Ardman B
Haseltine W
Sodroski J
Publication year
Publication venue
Journal of virology

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Snippet

The charged amino acids near or within the membrane-spanning region of the human immunodeficiency virus type 1 gp41 envelope glycoprotein were altered. Two mutants were defective for syncytium formation and virus replication even though levels of envelope …
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