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Bird et al., 2014 - Google Patents

Expansion of human and murine hematopoietic stem and progenitor cells ex vivo without genetic modification using MYC and Bcl-2 fusion proteins

Bird et al., 2014

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Document ID
6391487410992051475
Author
Bird G
Polsky A
Estes P
Hanlon T
Hamilton H
Morton J
Gutman J
Jimeno A
Turner B
Refaeli Y
Publication year
Publication venue
PloS one

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Snippet

The long-term repopulating hematopoietic stem cell (HSC) population can self-renew in vivo, support hematopoiesis for the lifetime of the individual, and is of critical importance in the context of bone marrow stem cell transplantation. The mechanisms that regulate the …
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