Nothing Special   »   [go: up one dir, main page]

Wolf et al., 2013 - Google Patents

Automated platform for sensor-based monitoring and controlled assays of living cells and tissues

Wolf et al., 2013

Document ID
617536054475889337
Author
Wolf P
Brischwein M
Kleinhans R
Demmel F
Schwarzenberger T
Pfister C
Wolf B
Publication year
Publication venue
Biosensors and Bioelectronics

External Links

Snippet

Cellular assays have become a fundamental technique in scientific research, pharmaceutical drug screening or toxicity testing. Therefore, the requirements of technical developments for automated assays raised in the same rate. A novel measuring platform …
Continue reading at www.sciencedirect.com (other versions)

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving viable micro-organisms
    • C12Q1/025Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving viable micro-organisms for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/36Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of biomass, e.g. colony counters or by turbidity measurements
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids

Similar Documents

Publication Publication Date Title
Wolf et al. Automated platform for sensor-based monitoring and controlled assays of living cells and tissues
Sung et al. Using physiologically-based pharmacokinetic-guided “body-on-a-chip” systems to predict mammalian response to drug and chemical exposure
Hulkower et al. Cell migration and invasion assays as tools for drug discovery
EP1465730B1 (en) An assay device and method for chemical or biological screening
Isherwood et al. Live cell in vitro and in vivo imaging applications: accelerating drug discovery
Wang et al. Microfabricated electrochemical cell-based biosensors for analysis of living cells in vitro
Molter et al. A microwell array device capable of measuring single-cell oxygen consumption rates
Müller et al. Measurement of respiration and acidification rates of mammalian cells in thermoplastic microfluidic devices
Zhang et al. Label-free estimation of therapeutic efficacy on 3D cancer spheres using convolutional neural network image analysis
EP2989460B1 (en) Method for a cell-based drug screening assay and the use thereof
Roper Cellular analysis using microfluidics
Hosokawa et al. Microfluidic device with chemical gradient for single-cell cytotoxicity assays
McKenzie et al. Real-time monitoring of cellular bioenergetics with a multianalyte screen-printed electrode
Horka et al. Lifetime of phosphorescence from nanoparticles yields accurate measurement of concentration of oxygen in microdroplets, allowing one to monitor the metabolism of bacteria
Alderman et al. A low-volume platform for cell-respirometric screening based on quenched-luminescence oxygen sensing
Lovitt et al. Cancer drug discovery: recent innovative approaches to tumor modeling
Voiculescu et al. Study of long-term viability of endothelial cells for lab-on-a-chip devices
CN101784895A (en) Method for predicting biological systems responses in hepatocytes
Han et al. Imaging technologies for microfluidic biochips
Polini et al. The convergence of high-tech emerging technologies into the next stage of organ-on-a-chips
Rösner et al. Sensors and techniques for on-line determination of cell viability in bioprocess monitoring
Schopf et al. Analytical methods to determine electrochemical factors in electrotaxis setups and their implications for experimental design
McCorry et al. Sensor technologies for quality control in engineered tissue manufacturing
Brischwein et al. Microphysiometry
Lei et al. Development of a micro-scale perfusion 3D cell culture biochip with an incorporated electrical impedance measurement scheme for the quantification of cell number in a 3D cell culture construct