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Borreca et al., 2020 - Google Patents

Transient upregulation of translational efficiency in prodromal and early symptomatic Tg2576 mice contributes to Aβ pathology

Borreca et al., 2020

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Document ID
6120037334262438396
Author
Borreca A
Valeri F
De Luca M
Ernst L
Russo A
Nobili A
Cordella A
Corsetti V
Amadoro G
Mercuri N
D'Amelio M
Ammassari-Teule M
Publication year
Publication venue
Neurobiology of disease

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Snippet

TG2576 mice show highest levels of the full length mutant Swedish Human Amyloid Precursor Protein (APPKM670/671LN) during prodromal and early sympotomatic stages. Interestingly, this occurs in association with the unbalanced expression of two of its RNA …
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