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Leong et al., 2018 - Google Patents

Doxorubicin conjugation and drug linker chemistry alter the intravenous and pulmonary pharmacokinetics of a PEGylated generation 4 polylysine dendrimer in rats

Leong et al., 2018

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Document ID
6119218561634348859
Author
Leong N
Mehta D
McLeod V
Kelly B
Pathak R
Owen D
Porter C
Kaminskas L
Publication year
Publication venue
Journal of pharmaceutical sciences

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Snippet

PEGylated polylysine dendrimers have demonstrated potential as inhalable drug delivery systems that can improve the treatment of lung cancers. Their treatment potential may be enhanced by developing constructs that display prolonged lung retention, together with …
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