Nothing Special   »   [go: up one dir, main page]

Hendrickson, 1999 - Google Patents

Cell cycle regulation of the MCM complex in initiation of DNA replication

Hendrickson, 1999

Document ID
5807407880899776352
Author
Hendrickson M
Publication year

External Links

Snippet

DNA replication is a fundamental step of the eukaryotic cell cycle that takes place once each cell cycle. The timing of S phase is regulated through the stepwise assembly of protein complexes at the origins of replication. The pre-replicative complex (pre-RC) contains the …
Continue reading at search.proquest.com (other versions)

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)

Similar Documents

Publication Publication Date Title
Yamaguchi et al. Structure and function of the human transcription elongation factor DSIF
Lutterbach et al. Hierarchical phosphorylation at N-terminal transformation-sensitive sites in c-Myc protein is regulated by mitogens and in mitosis
Chu et al. Basal phosphorylation of the PEST domain in IκBβ regulates its functional interaction with the c-rel proto-oncogene product
US7897741B2 (en) Cell cycle phase markers
Roy et al. The Drosophila poly (A) binding protein-interacting protein, dPaip2, is a novel effector of cell growth
Seshaiah et al. WRS-85D: A tryptophanyl-tRNA synthetase expressed to high levels in the developing Drosophila salivary gland
Frolova et al. Xenopus Cdc6 performs separate functions in initiating DNA replication
Hendrickson Cell cycle regulation of the MCM complex in initiation of DNA replication
Nishida et al. Identification of ZNF200 as a novel binding partner of histone H3 methyltransferase G9a
Pak The Drosophila melanogaster origin recognition complex
You Sensing and responding to DNA replication
Meyerson Human cyclin-dependent kinases and cell cycle regulation
Luciano HCF-1 functions as a coactivator for cellular and viral transcription factors
Van Oss Insights into the role of the Paf1 complex in promoting H2B monoubiquitylation
Rickert Functional and Biochemical Characterization of the cyclin C/CDK8 kinase
Krawitz The role of chromatin assembly factor-I in heterochromatin formation
Kaldis The CDK-Activating Kinase (CAK)
Bartosch The stability and turnover of Xenopus cyclin E
Ying Roles of MCM and ORC proteins during DNA replication: Studies in reconstituted cell-free systems from Xenopus laevis
Bond Poly (A) polymerase, the cell cycle and cell death
Silverman et al. Acetylation, activation, and toxicity: the role of ADA/GCN5 complex in transcription
Herbig Cloning and analysis of the human DNA replication initiation protein Cdc6
Dhillon Novel roles for cyclin E in cell growth and apoptosis
Gingras Regulation of the translational inhibitor 4E-BP1 by phosphorylation
DeCesare The N-terminus of the Cyclin Clb5 Confers the Specificity Required to Promote Pre-meiotic S-phase in Saccharomyces Cerevisiae