Shi et al., 2021 - Google Patents
Hypoxia-induced Nur77 activates PI3K/Akt signaling via suppression of Dicer/let-7i-5p to induce epithelial-to-mesenchymal transitionShi et al., 2021
View HTML- Document ID
- 5649353621422662597
- Author
- Shi Z
- To S
- Zhang S
- Deng S
- Artemenko M
- Zhang M
- Tang J
- Zeng J
- Wong A
- Publication year
- Publication venue
- Theranostics
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Snippet
Background: Colorectal cancer (CRC) and the associated metastatic lesions are reported to be hypoxic. Hypoxia is a common feature in the tumor microenvironment and a potent stimulant of CRC. We have identified a regulatory role of Nur77 on Akt activation to enhance …
- 102100015986 NR4A1 0 title abstract description 211
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- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay
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