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Wei et al., 2016 - Google Patents

Inhibiting cortical protein kinase A in spinal cord injured rats enhances efficacy of rehabilitative training

Wei et al., 2016

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Document ID
5369605186131336408
Author
Wei D
Hurd C
Galleguillos D
Singh J
Fenrich K
Webber C
Sipione S
Fouad K
Publication year
Publication venue
Experimental neurology

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Elevated levels of the second messenger molecule cyclic adenosine monophosphate (cAMP) are often associated with neuron sprouting and neurite extension (ie, neuroplasticity). Phosphokinase A (PKA) is a prominent downstream target of cAMP that has …
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    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
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    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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