Valencia Hernandez, 2020 - Google Patents
Inducing immunity to liver stage malaria through endogenous tissue resident memory cellsValencia Hernandez, 2020
View PDF- Document ID
- 5348097750639345724
- Author
- Valencia Hernandez A
- Publication year
External Links
Snippet
Tissue-resident memory CD8 T (TRM) cells provide effective tissue surveillance and can respond rapidly to infection due to their strategic location. Within the liver, TRM cells can induce effective protection against liver-stage Plasmodium infection. Recently, members …
- 210000004185 Liver 0 title abstract description 262
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/002—Protozoa antigens
- A61K39/015—Hemosporidia antigens, e.g. Plasmodium antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/21—Retroviridae, e.g. equine infectious anemia virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Silva et al. | A particulate saponin/TLR agonist vaccine adjuvant alters lymph flow and modulates adaptive immunity | |
Cockburn et al. | Malaria prevention: from immunological concepts to effective vaccines and protective antibodies | |
Caetano et al. | Requirement of UNC93B1 reveals a critical role for TLR7 in host resistance to primary infection with Trypanosoma cruzi | |
Mévélec et al. | Key limitations and new insights into the Toxoplasma gondii parasite stage switching for future vaccine development in human, livestock, and cats | |
Margaroni et al. | Vaccination with poly (D, L-lactide-co-glycolide) nanoparticles loaded with soluble Leishmania antigens and modified with a TNFα-mimicking peptide or monophosphoryl lipid A confers protection against experimental visceral leishmaniasis | |
Bucşan et al. | Setting the stage: The initial immune response to blood-stage parasites | |
Cherif et al. | Immunogenicity of novel nanoparticle-coated MSP-1 C-terminus malaria DNA vaccine using different routes of administration | |
Chandley et al. | Host-parasite interactions during Plasmodium infection: Implications for immunotherapies | |
Soon et al. | T-follicular helper cells in malaria infection and roles in antibody induction | |
Castro et al. | ASP-2/Trans-sialidase chimeric protein induces robust protective immunity in experimental models of Chagas’ disease | |
Othman et al. | OX40 stimulation enhances protective immune responses induced after vaccination with attenuated malaria parasites | |
Fernandez-Ruiz et al. | Harnessing liver-resident memory T cells for protection against malaria | |
US20210393760A1 (en) | Plasmodium with histamine releasing factor (hrf) deficiency for use as a vaccine | |
Nico et al. | NH36 and F3 antigen-primed dendritic cells show preserved migrating capabilities and CCR7 expression and F3 is effective in immunotherapy of visceral leishmaniasis | |
Valencia Hernandez | Inducing immunity to liver stage malaria through endogenous tissue resident memory cells | |
WO2013103362A1 (en) | Antigen-presenting platelets and methods of eliciting an immune response | |
Bhat et al. | Induction of cell-mediated immune responses to peptide antigens of P. vivax in microparticles using intranasal immunization | |
Teixeira et al. | Immunization with CSP and a RIG-I agonist is effective in inducing a functional and protective humoral response against Plasmodium | |
Bellamy | Investigating protective mechanisms of anti-sporozoite vaccines | |
US9907822B2 (en) | Therapeutic compositions and methods for treating infections | |
Thorburn | Understanding T cell and antibody-mediated immune mechanisms against malaria infection | |
McCaffery | Development of Novel Immunogens for Malaria Vaccines and Serosurveillance | |
Althubaiti | Protective Immunity Against Plasmodium Berghei Infection: Characterization of Liver Tissue Resident Memory CD8 T Cells According to Fine Specificities and Functional Attributes | |
Ssemaganda | Novel Approaches to Whole Parasite Blood-Stage Malaria Vaccine Development | |
Lefebvre | Fleet-footed soldiers: circulating memory CD8 T cells quickly enter the fray during malarial and bacterial infection of the liver |