Kaminskas et al., 2012 - Google Patents
Doxorubicin-conjugated PEGylated dendrimers show similar tumoricidal activity but lower systemic toxicity when compared to PEGylated liposome and solution …Kaminskas et al., 2012
- Document ID
- 4999911351826676736
- Author
- Kaminskas L
- McLeod V
- Kelly B
- Cullinane C
- Sberna G
- Williamson M
- Boyd B
- Owen D
- Porter C
- Publication year
- Publication venue
- Molecular pharmaceutics
External Links
Snippet
PEGylated polylysine dendrimers show promise as novel drug delivery systems with the potential to direct site specific deposition patterns and to reduce toxicity at nontarget sites. Here the activity and toxicity profiles of a generation 5 polylysine dendrimer with 50 …
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Classifications
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