Girgenti et al., 2021 - Google Patents
Transcriptomic organization of the human brain in post-traumatic stress disorderGirgenti et al., 2021
- Document ID
- 499473042317482172
- Author
- Girgenti M
- Wang J
- Ji D
- Cruz D
- Traumatic Stress Brain Research Group Alvarez Victor E. 3 13 17 Benedek David 18 Brady Christopher 3 13 17 Davis David A. 19 Holtzheimer Paul E. 3 16 Keane Terence M. 3 13 17 Kowell Neil 13 17 Logue Mark W. 3 13 17 McKee Ann 13 17 Marx Brian 3 13 17 Mash Deborah 19 Miller Mark W. 3 13 17 Scott William K. 20 Stein Thor 13 17 Ursano Robert 18 Wolf Erika J. 3 13 17
- Stein M
- Gelernter J
- Young K
- Huber B
- Williamson D
- Friedman M
- Krystal J
- Zhao H
- Duman R
- Publication year
- Publication venue
- Nature neuroscience
External Links
Snippet
Despite extensive study of the neurobiological correlates of post-traumatic stress disorder (PTSD), little is known about its molecular determinants. Here, differential gene expression and network analyses of four prefrontal cortex subregions from postmortem tissue of people …
- 201000008839 post-traumatic stress disease 0 title abstract description 232
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Hybridisation probes
- C12Q1/6883—Hybridisation probes for diseases caused by alterations of genetic material
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING; COUNTING
- G06F—ELECTRICAL DIGITAL DATA PROCESSING
- G06F19/00—Digital computing or data processing equipment or methods, specially adapted for specific applications
- G06F19/30—Medical informatics, i.e. computer-based analysis or dissemination of patient or disease data
- G06F19/34—Computer-assisted medical diagnosis or treatment, e.g. computerised prescription or delivery of medication or diets, computerised local control of medical devices, medical expert systems or telemedicine
- G06F19/345—Medical expert systems, neural networks or other automated diagnosis
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING; COUNTING
- G06Q—DATA PROCESSING SYSTEMS OR METHODS, SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL, SUPERVISORY OR FORECASTING PURPOSES; SYSTEMS OR METHODS SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL, SUPERVISORY OR FORECASTING PURPOSES, NOT OTHERWISE PROVIDED FOR
- G06Q50/00—Systems or methods specially adapted for a specific business sector, e.g. utilities or tourism
- G06Q50/10—Services
- G06Q50/22—Health care, e.g. hospitals; Social work
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING; COUNTING
- G06F—ELECTRICAL DIGITAL DATA PROCESSING
- G06F19/00—Digital computing or data processing equipment or methods, specially adapted for specific applications
- G06F19/30—Medical informatics, i.e. computer-based analysis or dissemination of patient or disease data
- G06F19/32—Medical data management, e.g. systems or protocols for archival or communication of medical images, computerised patient records or computerised general medical references
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING; COUNTING
- G06F—ELECTRICAL DIGITAL DATA PROCESSING
- G06F19/00—Digital computing or data processing equipment or methods, specially adapted for specific applications
- G06F19/30—Medical informatics, i.e. computer-based analysis or dissemination of patient or disease data
- G06F19/36—Computer-assisted acquisition of medical data, e.g. computerised clinical trials or questionnaires
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING; COUNTING
- G06F—ELECTRICAL DIGITAL DATA PROCESSING
- G06F19/00—Digital computing or data processing equipment or methods, specially adapted for specific applications
- G06F19/10—Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology
- G06F19/24—Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology for machine learning, data mining or biostatistics, e.g. pattern finding, knowledge discovery, rule extraction, correlation, clustering or classification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING; COUNTING
- G06Q—DATA PROCESSING SYSTEMS OR METHODS, SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL, SUPERVISORY OR FORECASTING PURPOSES; SYSTEMS OR METHODS SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL, SUPERVISORY OR FORECASTING PURPOSES, NOT OTHERWISE PROVIDED FOR
- G06Q50/00—Systems or methods specially adapted for a specific business sector, e.g. utilities or tourism
- G06Q50/01—Social networking
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Girgenti et al. | Transcriptomic organization of the human brain in post-traumatic stress disorder | |
Purves et al. | A major role for common genetic variation in anxiety disorders | |
Wu et al. | Genome-wide association study of medication-use and associated disease in the UK Biobank | |
Peña et al. | Early life stress alters transcriptomic patterning across reward circuitry in male and female mice | |
Suzuki et al. | Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population | |
Strawbridge et al. | Identification of novel genome-wide associations for suicidality in UK Biobank, genetic correlation with psychiatric disorders and polygenic association with completed suicide | |
Lane et al. | Biological and clinical insights from genetics of insomnia symptoms | |
Hammerschlag et al. | Genome-wide association analysis of insomnia complaints identifies risk genes and genetic overlap with psychiatric and metabolic traits | |
Wingo et al. | DICER1 and microRNA regulation in post-traumatic stress disorder with comorbid depression | |
Cohen et al. | Depressive symptoms and cortisol rhythmicity predict survival in patients with renal cell carcinoma: role of inflammatory signaling | |
Zhu et al. | Genome-wide profiling of DNA methylome and transcriptome in peripheral blood monocytes for major depression: A Monozygotic Discordant Twin Study | |
Zeidán-Chuliá et al. | Altered expression of Alzheimer’s disease-related genes in the cerebellum of autistic patients: a model for disrupted brain connectome and therapy | |
Zhou et al. | Multi-ancestry study of the genetics of problematic alcohol use in over 1 million individuals | |
Jørgensen et al. | Identification of genetic loci associated with nocturnal enuresis: a genome-wide association study | |
Malki et al. | Integrative mouse and human mRNA studies using WGCNA nominates novel candidate genes involved in the pathogenesis of major depressive disorder | |
Kamran et al. | Major depressive disorder: existing hypotheses about pathophysiological mechanisms and new genetic findings | |
Li et al. | Common variants on 6q16. 2, 12q24. 31 and 16p13. 3 are associated with major depressive disorder | |
Lin et al. | Cross-tissue exploration of genetic and epigenetic effects on brain gray matter in schizophrenia | |
Polimanti et al. | The interplay between risky sexual behaviors and alcohol dependence: genome-wide association and neuroimaging support for LHPP as a risk gene | |
Jalbrzikowski et al. | Transcriptome profiling of peripheral blood in 22q11. 2 deletion syndrome reveals functional pathways related to psychosis and autism spectrum disorder | |
Amanat et al. | Burden of rare variants in synaptic genes in patients with severe tinnitus: An exome based extreme phenotype study | |
Hicks et al. | Diurnal oscillations in human salivary microRNA and microbial transcription: Implications for human health and disease | |
Li et al. | Integrative analyses of major histocompatibility complex loci in the genome-wide association studies of major depressive disorder | |
Zhu et al. | Identification of lncRNAs involved in biological regulation in early age-related macular degeneration | |
Yamagata et al. | Identification of commonly altered genes between in major depressive disorder and a mouse model of depression |