Gottschalk et al., 1998 - Google Patents
Presynaptic modulation of synaptic transmission and plasticity by brain-derived neurotrophic factor in the developing hippocampusGottschalk et al., 1998
View PDF- Document ID
- 4749302484245777097
- Author
- Gottschalk W
- Pozzo-Miller L
- Figurov A
- Lu B
- Publication year
- Publication venue
- Journal of Neuroscience
External Links
Snippet
In addition to the regulation of neuronal survival and differentiation, neurotrophins may play a role in synapse development and plasticity. Application of brain-derived neurotrophic factor (BDNF) promotes long-term potentiation (LTP) in CA1 synapses of neonatal …
- 102000004219 Brain-Derived Neurotrophic Factor 0 title abstract description 263
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic, hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Gottschalk et al. | Presynaptic modulation of synaptic transmission and plasticity by brain-derived neurotrophic factor in the developing hippocampus | |
Pozzo-Miller et al. | Impairments in high-frequency transmission, synaptic vesicle docking, and synaptic protein distribution in the hippocampus of BDNF knockout mice | |
Gonon | Prolonged and extrasynaptic excitatory action of dopamine mediated by D1 receptors in the rat striatum in vivo | |
Kuczewski et al. | Backpropagating action potentials trigger dendritic release of BDNF during spontaneous network activity | |
Tanaka et al. | Inhibition of GABAA synaptic responses by brain-derived neurotrophic factor (BDNF) in rat hippocampus | |
Floresco et al. | Dopaminergic regulation of inhibitory and excitatory transmission in the basolateral amygdala–prefrontal cortical pathway | |
Norris et al. | Reversal of age-related alterations in synaptic plasticity by blockade of L-type Ca2+ channels | |
Chen et al. | Relative contribution of endogenous neurotrophins in hippocampal long-term potentiation | |
Akaneya et al. | Brain-derived neurotrophic factor enhances long-term potentiation in rat visual cortex | |
Chavas et al. | Coexistence of excitatory and inhibitory GABA synapses in the cerebellar interneuron network | |
Han et al. | Role of cAMP response element-binding protein in the rat locus ceruleus: regulation of neuronal activity and opiate withdrawal behaviors | |
Hickey et al. | Optoactivation of locus ceruleus neurons evokes bidirectional changes in thermal nociception in rats | |
Kittelberger et al. | Lesions of an avian forebrain nucleus that disrupt song development alter synaptic connectivity and transmission in the vocal premotor pathway | |
Marinelli et al. | Enhanced vulnerability to cocaine self-administration is associated with elevated impulse activity of midbrain dopamine neurons | |
Rutherford et al. | Brain-derived neurotrophic factor mediates the activity-dependent regulation of inhibition in neocortical cultures | |
Wang et al. | Localized synaptic actions of neurotrophin-4 | |
Chen et al. | Pituitary adenylyl cyclase-activating peptide: a pivotal modulator of glutamatergic regulation of the suprachiasmatic circadian clock | |
Cruikshank et al. | Thalamic control of layer 1 circuits in prefrontal cortex | |
Lockhart et al. | Nerve growth factor modulates synaptic transmission between sympathetic neurons and cardiac myocytes | |
Garcia et al. | Dual effect of high-frequency stimulation on subthalamic neuron activity | |
Partridge et al. | Regional and postnatal heterogeneity of activity-dependent long-term changes in synaptic efficacy in the dorsal striatum | |
Weisskopf et al. | L-type voltage-gated calcium channels mediate NMDA-independent associative long-term potentiation at thalamic input synapses to the amygdala | |
Kerr et al. | Brain-derived neurotrophic factor modulates nociceptive sensory inputs and NMDA-evoked responses in the rat spinal cord | |
Gottschalk et al. | Signaling mechanisms mediating BDNF modulation of synaptic plasticity in the hippocampus | |
Lodovichi et al. | Effects of neurotrophins on cortical plasticity: same or different? |