Want, 2022 - Google Patents
A functional role for brain-derived neurotrophic factor from circulating blood platelets and potential neuroprotective applicationsWant, 2022
View PDF- Document ID
- 420711565359560350
- Author
- Want A
- Publication year
External Links
Snippet
Brain-derived neurotrophic factor (BDNF) is well known as a major effector of synaptic plasticity and for its role as a neuroprotectant. It has been extensively investigated as a possible treatment for neurodegenerative conditions such as glaucoma, a condition …
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5082—Supracellular entities, e.g. tissue, organisms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Kim et al. | YAP/TAZ regulates sprouting angiogenesis and vascular barrier maturation | |
Ou et al. | Synaptic pathology and therapeutic repair in adult retinoschisis mouse by AAV-RS1 transfer | |
Horn et al. | DCC expression by neurons regulates synaptic plasticity in the adult brain | |
Alvarez et al. | Genetic determinants of hyaloid and retinal vasculature in zebrafish | |
Li et al. | DSCAM promotes refinement in the mouse retina through cell death and restriction of exploring dendrites | |
Chuang et al. | Chloride intracellular channel 4 is critical for the epithelial morphogenesis of RPE cells and retinal attachment | |
Banh et al. | Lens-specific expression of TGF-β induces anterior subcapsular cataract formation in the absence of Smad3 | |
Fu et al. | Ectopic vesicular glutamate release at the optic nerve head and axon loss in mouse experimental glaucoma | |
Westcot et al. | Protein-Trap insertional mutagenesis uncovers new genes involved in zebrafish skin development, including a neuregulin 2a-Based ErbB signaling pathway required during median fin fold morphogenesis | |
Tapia et al. | Subtype-specific survival and regeneration of retinal ganglion cells in response to injury | |
US20110065645A1 (en) | Compositions and Methods for Modulating Neuron Degeneration and Neuron Guidance | |
Want | A functional role for brain-derived neurotrophic factor from circulating blood platelets and potential neuroprotective applications | |
Jeon et al. | Deciphering perivascular macrophages and microglia in the retinal ganglion cell layers | |
Pereira | Focusing on metabolomic dysregulation and modulation of retinal metabolism to develop novel therapeutic strategies for diabetic retinopathy | |
Kim et al. | PLCγ1 in dopamine neurons critically regulates striatal dopamine release via VMAT2 and synapsin III | |
US9415090B2 (en) | VEGF-D/VEGFR2/3-mediated regulation of dendrites | |
CA2834832C (en) | Vegf-d/vegfr2/3-mediated regulation of dendrites | |
Luo et al. | Superior colliculus-projecting GABAergic retinal ganglion cells mediate looming-evoked flight response | |
Wang | A spinal circuit for thermal pain regulated by ErbB4 | |
Malhi | Use of SRPK1 inhibitors for the treatment of Diabetic Retinopathy | |
Abed | The Role of Transcription Factors in RGC Development, Maintenance, and Survival | |
Marola | Mechanisms of Glaucoma-Relevant Retinal Ganglion Cell Death | |
Abed | The Role of Transcription Factors in Retinal Ganglion Cell Development, Maintenance, and Survival | |
Gurdita | Investigating the Mechanisms That Regulate Rod Photoreceptor Positioning and Connectivity in the Developing Murine Retina | |
Nishijima et al. | Membrane-associated shortened Trk receptors promote neuroprotection and robust axon regeneration without ligands |