FLURBIPROFEN

(flure BI proe fen) Brand: Ansaid

What is the most significant information I must know about flurbiprofen?

• This medication may reason life-threatening heart or circulation problems such as heart onslaught or stroke. Do not use flurbiprofen just till or after having heart bypass surgery (also called coronary artery bypass graft, or CABG).

• Get abnormal medical help if you have chest pain, weakness, shortness of breath, slurred speech, or problems with vision or balance.

• This medication may also reason serious effects on the stomach or intestines, including bleeding or perforation (forming of a hole). These conditions can be fatal and can occur without warning while you are taking flurbiprofen, especially in older adults.

• Call your doctor at once if you have symptoms of stomach bleeding such as black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds.

What is flurbiprofen?

• Flurbiprofen is in a group of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Flurbiprofen works by reducing hormones that reason inflammation and pain in the body.

• Flurbiprofen is used to treat pain or inflammation caused by arthritis.

• Flurbiprofen may also be used for another purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till taking flurbiprofen?

• This medication may reason life-threatening heart or circulation problems such as heart onslaught or stroke, especially if you use it long term. Do not use flurbiprofen just till or after heart bypass surgery (coronary artery bypass graft, or CABG).

• Do not use this medicine if you are allergic to flurbiprofen, or if you have:

· severe kidney malady; or

· a history of allergic reaction to aspirin or another NSAIDs.

• If you have any of these another conditions, you may need a flurbiprofen doze adjustment or particular tests:

· a history of heart onslaught, stroke, or blood clot;

· heart malady, congestive heart failure, tall blood pressure;

· a history of stomach ulcer or bleeding;

· liver or kidney disease;

· asthma;

· polyps in your nose;

· a bleeding or blood clotting mess; or

· if you smoke.

• FDA pregnancy category C. Speak your doctor if you are pregnant or plan to become pregnant during treatment. Taking flurbiprofen during the recent 3 months of pregnancy may harm the unborn baby. Do not take flurbiprofen during pregnancy unless your doctor has told you to.

• Flurbiprofen can pass into breast milk and may harm a nursing child. Do not use this medicine without telling your doctor if you are breast-feeding a baby.

• Do not give this medication to a baby without the advice of a doctor.

How must I take flurbiprofen?

• Take exactly as predesigned by your doctor. Do not take in larger or less amounts or for longer than recommended. Follow the directions on your prescription label.

• The maximum amount of flurbiprofen for adults is 400 milligrams (mg) for day. Know the amount of flurbiprofen in the specific product you are taking.

• If you take flurbiprofen for a long period of time, your doctor may want to check you on a regular basis to create certain this medicine is not causing deleterious effects. Do not miss any scheduled appointments.

• Store at room temperature, away from moisture, heat, and light.

What happens if I miss a dose?

• Take the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include nausea, vomiting, stomach pain, dizziness, drowsiness, black or bloody stools, coughing up blood, urinating smaller than normal or not at all, shallow breathing, and fainting.

What must I avoid while taking flurbiprofen?

• Ask a doctor or pharmacist till using any another cool, allergy, or pain medication. Much medicines accessible over the counter contain medicines similar to flurbiprofen (such as aspirin, ibuprofen, ketoprofen, or naproxen). Taking determined commodity together can reason you to get too many of this type of medicine. Check the label to see if a medication contains aspirin, ibuprofen, ketoprofen, or naproxen.

• Avoid drinking alcohol. It may magnify your risk of stomach bleeding.

What are the possible side effects of flurbiprofen?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Stop taking flurbiprofen and search medical attention or call your doctor at once if you have any of these serious side effects:

· chest pain, weakness, shortness of breath, slurred speech, problems with vision or balance;

· black, bloody, or tarry stools, coughing up blood or vomit that looks like coffee grounds;

· urinating smaller than normal or not at all;

· pain, burning, or bleeding when you urinate;

· swelling, rapid weight gain;

· nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

· fever, sore throat, and headache with a severe blistering, peeling, and red skin rash; or

· bruising, severe tingling, numbness, pain, muscle weakness.

• Smaller serious side effects may include:

· upset stomach, mild heartburn or stomach pain, diarrhea, constipation; bloating, gas;

· dizziness, headache, nervousness;

· skin itching or rash;

· dry mouth;

· heighten sweating, runny nose;

· blurred vision; or

· ringing in your ears.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect flurbiprofen?

• Speak your doctor if you are taking an antidepressant such as citalopram (Celexa), duloxetine (Cymbalta), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, Symbyax), fluvoxamine (Luvox), paroxetine (Paxil), sertraline (Zoloft), or venlafaxine (Effexor). Taking any of these drugs with flurbiprofen may reason you to bruise or bleed easily.

• Speak your doctor about all another medicines you use, especially:

· a blood thinner such as warfarin (Coumadin;

· a diuretic (water pill) such as furosemide (Lasix);

· cyclosporine (Gengraf, Neoral, Sandimmune);

· lithium (Eskalith, Lithobid);

· methotrexate (Rheumatrex, Trexall);

· steroids (prednisone and others);

· aspirin or another NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen (Motrin, Advil), diclofenac (Cataflam, Voltaren), etodolac (Lodine), indomethacin (Indocin), meloxicam (Mobic), nabumetone (Relafen), naproxen (Aleve, Naprosyn), piroxicam (Feldene), and others;

· an ACE inhibitor such as benazepril (Lotensin), enalapril (Vasotec), lisinopril (Prinivil, Zestril), quinapril (Accupril), ramipril (Altace), and others; or

· a beta-blocker such as atenolol (Tenormin, Tenoretic), carvedilol (Coreg), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), and others.

• This list is not complete and another drugs may interact with flurbiprofen. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about flurbiprofen.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

(41)