DICLOFENAC

(dye KLOE fen ak) Brand: Cambia, Cataflam, Voltaren, Voltaren-XR, Zipsor

What is the most significant information I must know about diclofenac?

• You must not use this medication if you have a history of allergic reaction to aspirin or NSAIDs (non-steroidal anti-inflammatory drugs).

• Diclofenac may magnify your risk of heart onslaught or stroke, especially if you use it long term or have heart malady. Do not use this medication just till or after heart bypass surgery (coronary artery bypass graft, or CABG).

• Diclofenac may also reason stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are taking diclofenac.

What is diclofenac?

• Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID). This medication works by reducing substances in the body that reason pain and inflammation.

• Diclofenac is used to treat pain or inflammation caused by arthritis or ankylosing spondylitis.

• Diclofenac powder (Cambia) is used to treat a migraine headache onslaught. Do not use this medicine to treat a cluster headache. Cambia will only treat a headache that has already begun. It will not prevent headaches or reduce the number of attacks.

• Diclofenac may also be used for purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till taking diclofenac?

• You must not use this medication if you have a history of allergic reaction to aspirin or NSAIDs (non-steroidal anti-inflammatory drugs).

• Diclofenac may magnify your risk of heart onslaught or stroke, especially if you use it long term or have heart malady. Do not use this medication just till or after heart bypass surgery (coronary artery bypass graft, or CABG).

• Diclofenac may also reason stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are taking diclofenac.

• To create certain diclofenac is safety for you, speak your doctor if you have:

· heart malady, tall blood pressure, or history of heart onslaught, stroke, or blood clot;

· a history of stomach ulcers or bleeding;

· liver or kidney disease,

· asthma;

· polyps in your nose;

· a bleeding or blood clotting mess; or

· if you smoke.

• FDA pregnancy category D. Speak your doctor if you are pregnant or plan to become pregnant during treatment. Taking diclofenac during the recent 3 months of pregnancy may harm the unborn baby. Do not take diclofenac during pregnancy unless your doctor has told you to.

• It is not known whether diclofenac passes into breast milk or if it could harm a nursing child. You must not breast-feed while using this medicine.

• Do not give this medication to a baby younger than 18 years old without medical advice.

How must I take diclofenac?

• Follow all directions on your prescription label. Do not take this medication in larger or less amounts or for longer than recommended.

• If you switch brands of diclofenac, your doze needs may change. Follow your doctor's instructions about how many medication to take.

• Do not crush, chew, or interrupt an extended-release tablet. Swallow it intact.

• Dissolve the diclofenac powder (Cambia) with 1 to 2 ounces of water. Do not use any another type of liquid. Stir this mixture and drink all of it right away. Diclofenac powder works excellent if you take it on an empty stomach.

• Call your doctor if your headache does not completely go away after taking Cambia. Do not take a second doze of diclofenac powder without your doctor's advice.

• Do not crush, chew, or interrupt an enteric coated pill. Swallow it intact. The pill has a particular coating to protect your stomach. Breaking the pill will hurt this coating.

• If you use diclofenac long-term, you may need frequent medical trials at your doctor's office.

• Store at room temperature away from moisture and heat.

What happens if I miss a dose?

• Take the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.

What must I avoid while taking diclofenac?

• Ask a doctor or pharmacist till using any cool, allergy, or pain medicine. Much medicines accessible over the counter contain aspirin or another medicines similar to diclofenac. Taking determined commodity together can reason you to get too many of this type of medicine. Check the label to see if a medication contains aspirin, ibuprofen, ketoprofen, or naproxen.

• Avoid drinking alcohol. It may magnify your risk of stomach bleeding.

• Avoid exposure to sunlight or tanning beds. Diclofenac can create you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

What are the possible side effects of diclofenac?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Stop using diclofenac and call your doctor at once if you have:

· sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, problems with vision or balance;

· chest pain, sudden cough, wheezing, rapid breathing;

· bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;

· few or no urinating;

· swelling, rapid weight gain;

· nausea, upper stomach pain, itching, diarrhea, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

· bruising, severe tingling, numbness, pain, muscle weakness;

· pale skin, feeling light-headed or short of breath, rapid heart course, trouble concentrating;

· fever, neck stiffness, heighten sensitivity to easy, purple spots on the skin, and/or seizure (convulsions); or

· severe skin reaction -- fever, sore throat, swelling in your person or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the person or upper body) and causes blistering and peeling.

• General side effects may include:

· upset stomach, mild heartburn or stomach pain, bloating, gas;

· mild diarrhea, constipation;

· dizziness, mild headache;

· mild skin rash; or

· ringing in your ears.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect diclofenac?

• Ask your doctor till using diclofenac if you take an antidepressant such as citalopram, escitalopram, fluoxetine (Prozac), fluvoxamine, paroxetine, sertraline (Zoloft), trazodone, or vilazodone. Taking any of these medicines with an NSAID may reason you to bruise or bleed easily.

• Speak your doctor about all medicines you use, and those you start or stop using during your treatment with diclofenac, especially:

· cyclosporine;

· lithium;

· methotrexate;

· rifampin;

· antifungal medication--fluconazole, voriconazole;

· a blood thinner (warfarin, Coumadin);

· a diuretic or "water pill";

· heart or blood pressure medication--amiodarone, benazepril, captopril, enalapril, fosinopril, lisinopril, moexipril, perindopril, quinapril, ramipril, or trandolapril; or

· another NSAIDs--aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.

• This list is not complete. Another drugs may interact with diclofenac, including prescription and over-the-counter medicines, vitamins, and herbal commodity. Not all possible interactions are listed in this medicine manual.

Where can I get more information?

• Your pharmacist can provide more information about diclofenac.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.