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Oncology & Cancer news
Oncology & Cancer
Study shows historic redlining—a form of structural racism—affects survival in young people with cancer
A recent study indicates that children and young adults with cancer face an elevated risk of dying if they live in previously redlined neighborhoods—residential areas marked in the 1920s–1930s by lenders as undesirable ...
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Medications
Blood test could guide use of anti-inflammatory drug celecoxib to reduce risk of colon cancer recurrence
A data analysis from a randomized clinical trial for stage 3 colon cancer patients by investigators at Dana-Farber Brigham Cancer Center found that patients with evidence of residual cancer in their blood after surgery to ...
6 minutes ago
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Scientists uncover how cancer cells hijack T-cells, making it harder for the body to fight back
Research led by the Chiba Cancer Center Research Institute in Japan has discovered a surprising way cancer evades the immune system. It essentially hacks the immune cells, transferring its own faulty mitochondrial DNA (mtDNA) ...
Proof-of-concept study dissolves clusters of breast cancer cells to prevent metastases
Certain tumor types do not remain at their point of origin but spread throughout the body and form metastases. This is because the primary tumor continuously releases cancer cells into the blood. These circulating tumor cells ...
Jan 24, 2025
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Targeting potassium channel shows promise for treating brain tumors in children
Scientists at The Hospital for Sick Children (SickKids) have identified a key gene that could lead to next-generation treatments for medulloblastoma, the most common malignant brain tumor in children.
Jan 24, 2025
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Using AI to predict the after-effects of brain tumor surgery
Patients with a glioma, a type of malignant brain tumor, can suffer from cognitive problems after surgery. However, the true effect of surgery on complex cognitive tasks is not known. To predict the effects of surgery on ...
Jan 24, 2025
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Lower dexamethasone dose does not impair survival in multiple myeloma
For patients with newly diagnosed multiple myeloma (NDMM) receiving dexamethasone induction, dose reductions do not negatively impact survival, according to a study published online Jan. 2 in Blood.
Jan 24, 2025
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Researchers are developing personalized vaccines that target cancer tumors
Vaccines are helpful in protecting against the flu and COVID-19, but could they also play a role in the fight against cancer? Imagine a future where every cancer treatment is personalized to each patient, precisely targeting ...
Jan 24, 2025
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Tool gives more accurate estimates of recurrence risk and individual chemotherapy benefit in node-positive breast cancer
A new statistical tool that combines multiple clinical and pathologic factors with a patient's 21-gene Oncotype DX Breast Recurrence Score result provides more accurate estimates about that patient's breast cancer prognosis ...
Jan 24, 2025
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Study reveals novel insights into the molecular pathology of esophageal squamous cell carcinoma
Esophageal squamous cell carcinoma (ESCC) is a highly aggressive malignancy with poor prognosis, and understanding the molecular mechanisms underlying its progression is crucial for developing effective therapies.
Jan 24, 2025
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New dual stem cell therapy developed to treat brain metastasis in patients with non-small cell lung cancer
New research highlights the promise of a novel stem cell treatment strategy for leptomeningeal brain metastasis (LBM), a severe form of metastatic brain cancer that spreads to membranes surrounding the brain and spinal cord ...
Jan 23, 2025
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Immunotherapy that combines hormone and topical treatment offers new hope for melanoma and breast cancer
A research team at the Medical University of Vienna led by Maria Sibilia has investigated a new combination therapy against cancer. This therapy employs systemic administration of the tissue hormone interferon-I combined ...
Jan 23, 2025
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Unlocking new insights into hereditary ovarian cancer risk
Researchers at Peter Mac have uncovered potential new heredity genes that might be responsible for causing one of the most prevalent and deadliest forms of ovarian cancer. Their work is published in the journal npj Genomic ...
Jan 23, 2025
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How the chemotherapy drug sorafenib triggers muscle wasting through cell remodeling
Chemotherapeutic agents are often used to treat cancer. They combat tumor growth, but also have a number of undesirable side effects. One of these is severe muscle wasting, known as chemotherapy-induced cachexia. This chronic ...
Jan 23, 2025
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Study reveals unique features of early-onset colorectal cancer in racial and ethnic minorities
Colorectal cancer is typically diagnosed after age 50, but in recent years the disease has been increasingly found in younger people and disproportionately affecting racial and ethnic minorities.
Jan 23, 2025
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Chemotherapy and immunotherapy combo shows promise for aggressive lymphoma
An international team of doctors led by Joshua Brody, MD, Director of the Lymphoma Immunotherapy Program at The Tisch Cancer Institute at Mount Sinai, has made a major breakthrough in treating a common and challenging form ...
Jan 23, 2025
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Perioperative chemo with certain chemotherapy drugs ups survival in resectable esophageal cancer
For patients with resectable esophageal adenocarcinoma, perioperative chemotherapy with fluorouracil, leucovorin, oxaliplatin, and docetaxel (FLOT) leads to improved survival compared with preoperative chemoradiotherapy, ...
Jan 23, 2025
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Q&A: Researcher discusses identifying new treatments for pediatric brain cancer
Rakesh Jain Ph.D., Director of the E.L. Steele Laboratories for Tumor Biology at Massachusetts General Hospital and A. Werk Cook Professor of Radiation Oncology at Harvard Medical School, is senior author of a new study in ...
Jan 23, 2025
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Genetic insights reveal pathways of childhood kidney cancer development
Genetically tailored treatment plans for children with a type of kidney cancer could help provide the most effective care while minimizing side effects as much as possible.
Jan 23, 2025
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Olaparib could be a safe, effective maintenance therapy in some ovarian cancer patients
Ovarian cancer has seen a significant shift in its treatment paradigm with the introduction of poly (ADP-ribose) polymerase (PARP) inhibitors, which are now standard in the maintenance setting following first-line chemotherapy.
Jan 23, 2025
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Metronomic chemotherapy: A promising approach for pediatric neuroblastoma
Neuroblastoma is the most common extracranial solid tumor in children, with nearly 50% of cases diagnosed at an advanced stage, often with metastatic disease. Despite advances in treatment, survival rates for high-risk and ...
Jan 23, 2025
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Melanoma metastasis: Research unveils the cell death pathway in bone
Melanoma, one of the most aggressive forms of skin cancer, often metastasizes to bones, causing severe bone loss, an increased risk of fractures, and significant pain. Bone metastasis is associated with poor survival rates ...
Jan 23, 2025
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Drug candidate eliminates breast cancer tumors in mice in a single dose
Despite significant therapeutic advances, breast cancer remains a leading cause of cancer-related death in women. Treatment typically involves surgery and follow-up hormone therapy, but late effects of these treatments include ...
Jan 22, 2025
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Melanoma study identifies a mechanism for eliminating harmful cells from cancer treatment
After treating a tumor with chemotherapy and radiotherapy, cells known as senescent cells can appear. These are cells that do not divide, are involved in the aging process, and are resistant to cell death, but are still metabolically ...
Jan 22, 2025
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Injectable supramolecular hydrogel shows promise for neoadjuvant immunotherapy of triple-negative breast cancer
The efficacy of immunotherapy against triple-negative breast cancer (TNBC) heavily relies on intratumoral infiltration of cytotoxic T lymphocytes (CTLs). Although neoadjuvant chemotherapy together with immunotherapy has been ...
Jan 22, 2025
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