Dynorphinum
Appearance
Dynorphina sunt classis peptidorum opioidi, quae ex proteino praecursore prodynorphino emanat. Prodynorphino ope enzymi proproteini convertasis 2 (PC2) secto proteina activa liberantur: dynorphinum A, dynorphinum B, α-/β-neoendorphina[1]. Inveniuntur dynorphina in vesiculis terminorum synapticorum[2].
Notae
[recensere | fontem recensere]- ↑ Day R., Lazure C., Basak A., Boudreault A., Limperis P., Dong W., Lindberg I. (Ian 1998). "Prodynorphin processing by proprotein convertase 2. Cleavage at single basic residues and enhanced processing in the presence of carboxypeptidase activity". The journal of biological chemistry 273 (2): 829-32.
- ↑ Yakovleva T., Bazov I., Cebers G., Marinova Z., Hara Y., Ahmed A., Vlaskovska M., Johansson B., Hochgeschwender U., Singh I. N., Bruce-Keller A. J., Hurd Y. L., Kaneko T., Terenius L., Ekström T. J., Hauser K. F., Pickel V. M., Bakalkin G. (Oct 2006). "Prodynorphin storage and processing in axon terminals and dendrites". FASEB journal 20 (12): 2124-6.