Research article by Lakshmi Sivasubramanian
A simple, efficient and reproducible method for the determination of entacapone in tablets has be... more A simple, efficient and reproducible method for the determination of entacapone in tablets has been developed using reverse phase high performance liquid chromatographic method. The elution was done using a mobile phase consisting of acetonitrile and methanol (50:50 v/v) pH adjusted to 2.75 with ortho-phosphoric acid on inertsil C18, 4.6 × 250 mm analytical column with flow rate of 1 ml/min with detection at 315 nm. An external standard calibration method was employed for quantitation. The elution time was 3.15 ± 0.02 min. The linearity was 2-12 µg/ ml for entacapone.
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An accurate, simple, reproducible and sensitive method for the determination of paracetamol, ceti... more An accurate, simple, reproducible and sensitive method for the determination of paracetamol, cetirizine and pseudoephedrine was developed and validated. Paracetamol, cetirizine and pseudoephedrine were separated using a Hypersil C18 column by isocratic elution ...
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Research article by Lakshmi Sivasubramanian
Papers by Lakshmi Sivasubramanian