Papers by Nikolaos Baikoussis
Interdisciplinary CardioVascular and Thoracic Surgery
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Heart Lung and Circulation, Jul 1, 2019
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European Journal of Cardio-Thoracic Surgery, Jun 23, 2020
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The Annals of Thoracic Surgery, Nov 1, 2020
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The Annals of Thoracic Surgery, Apr 1, 2020
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The Annals of Thoracic Surgery, 2019
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Annals of Cardiac Anaesthesia, 2020
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Journal of Hypertension, 2019
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Oncomedicine, 2017
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International Journal of Molecular Sciences
Extensive research has been conducted to elucidate and substantiate the crucial role of the Renin... more Extensive research has been conducted to elucidate and substantiate the crucial role of the Renin-Angiotensin System (RAS) in the pathogenesis of hypertension, cardiovascular disorders, and renal diseases. Furthermore, the role of oxidative stress in maintaining vascular balance has been well established. It has been observed that many of the cellular effects induced by Angiotensin II (Ang II) are facilitated by reactive oxygen species (ROS) produced by nicotinamide adenine dinucleotide phosphate (NADPH) oxidase. In this paper, we present a comprehensive overview of the role of ROS in the physiology of human blood vessels, specifically focusing on its interaction with RAS. Moreover, we delve into the mechanisms by which clinical interventions targeting RAS influence redox signaling in the vascular wall.
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INTRODUCTION: The neurological alterations are common complications and consists a significant ca... more INTRODUCTION: The neurological alterations are common complications and consists a significant cause of mortality and morbidity after heart surgery. For the central nervous system monitoring during cardiac surgery are used the EEG, the somato-sensitive evocated potentials (SSEP) and recently the regional saturation of oxygen (rSO2) witch measures approximately the saturation of the cerebral venous blood, reflected the equilibration between offer and demand of oxygen. AIM: The aim of our research is the study of the baseline rSO2 range in a group of patient undergone on cardiac surgery, the possible factors influencing the rSO2 and its alterations during the operation. We would like also to study the effect of the extracorporeal circulation and the cross clamp time on the patient outcome. MATERIAL AND METHODS: We studied 100 patients undergone on selected cardiac surgery intervention. Of them, 78 underwent on coronary-artery bypass grafting, 36 of them underwent on off-pump coronary ...
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Artery Research, 2020
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Journal of Cardiothoracic Surgery
Background From a variety of ring types, semirigid ring is more preferred for mitral annuloplasty... more Background From a variety of ring types, semirigid ring is more preferred for mitral annuloplasty during mitral valve repair particularly in patients whose native mitral saddle shape annulus is well maintained. During mitral annuloplasty artificial chord implantation with the appropriate neochord length is surgically challenging. We present our experience of using the Memo 3D ReChord, a semirigid ring with additional chordal guiding system for mitral valve repair. Patients and methods From September 2018 to February 2020, we successfully treated ten patients with severe (4+/4+) degenerative mitral valve regurgitation due to posterior leaflet prolapse with chordal rupture with the implantation Memo 3D ReChord and neo-chords. Results We implanted from one to three neo-chords and always a ring in our patients. None of the patients had any residual mitral valve regurgitation at the end of the repair and on their discharge evaluated through transesophageal and transthoracic echocardiogra...
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Annals of Cardiac Anaesthesia, 2015
Lipomatous hypertrophy of the interatrial septum (LHIS) is an uncommon cause of superior vena cav... more Lipomatous hypertrophy of the interatrial septum (LHIS) is an uncommon cause of superior vena cava syndrome (SVCS). Fibrosing mediastinal lymphadenopathy is another cause of SVCS. We present a 65-year-old female patient with a history of tuberculosis (TB) and the coexistence of LHIS and fibrosing mediastinitis due to TB of the lung. Fibrosing or sclerosing mediastinitis is a rare entity with few cases published in the western literature. She presented with mild symptomatology of SVCS and she underwent on transthoracic and transesophageal echocardiography, computed tomography scan, magnetic resonance imaging, and venography. Due to the development of an abundant collateral venous system seen on venography and her negation for any treatment, she did not undergo yet on any intervention. To our knowledge, this is the first case reported in the international bibliography in which LHIS and sclerosing lymphadenopathy are simultaneously diagnosed in the same patient.
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Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese, 2011
Kolokotroni 4, Messatida 26500 Patras, Greece e-mail: ngbaik@yahoo.com
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European review for medical and pharmacological sciences, 2011
Corresponding Author: Nikolaos G. Baikoussis, MD; e-mail: ngbaik@yahoo.com initial computed tomog... more Corresponding Author: Nikolaos G. Baikoussis, MD; e-mail: ngbaik@yahoo.com initial computed tomography (CT) are representative of thoracic trauma. Chest x-ray (Figure 1a) revealed a well circumscribed opacity in the left haemithorax recommending the contrast mediated thorax computed tomography (CT). The CT immediately performed shown left rib fractures and a D-shaped opacity in the left side of the thorax suggesting extrapleural hematoma, which was caused by continuous bleeding of an intercostal artery (Figure 1b). The initial conservative treatment (transfusion, anticoagulation reverse and cardiopulmonary support) was followed because of anticoagulation therapy and the presence of comorbidities; high risk for a routine tho2011; 15: 978-979
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Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese, 2011
Acute cerebral embolism or cerebral aneurysm formation as a consequence of left atrial myxomas ha... more Acute cerebral embolism or cerebral aneurysm formation as a consequence of left atrial myxomas has been well documented, but the formation of multiple cerebral aneurysms resulting from atrial myxoma is a very rare neurological complication. We present the case of a 72-year-old-woman with a cardiac myxoma who suffered multiple cerebral mycotic aneurysms. After experiencing both vertigo and a sudden collapse accompanied by loss of consciousness, she underwent cerebral computed tomography (CT) and magnetic resonance imaging (MRI) examinations, which revealed multiple cerebral mycotic aneurysms of various dimensions and a large cyst, as a result of a previous haemorrhage. Embolisation was performed in large aneurysms of the circle of Willis but not in the one located in the periphery, and re-examination for a cardiac intervention a month later was indicated. The risk of cerebral haemorrhage was considered high; thus she was not operated on. Conservative treatment followed. Two years aft...
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Annals of Cardiac Anaesthesia, 2016
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Journal of cardiothoracic surgery, Jan 11, 2016
The aim of this study is to see how the sutureless, stentless, Perceval S aortic valves behave wh... more The aim of this study is to see how the sutureless, stentless, Perceval S aortic valves behave when implanted in elderly patients with small aortic root and the comparison with a second group of patients with similar characteristics where a conventional stented bioprosthesis was implanted. This is a prospective randomized institutional study. Our material is composed from 25 patients who underwent aortic valve replacement with sutureless self-anchoring Perceval S valve implantation (LivaNova), compared with 25 patients with conventional stented biological prosthesis implanted (soprano LivaNova group). The two groups of patients have similar demographic and medical characteristics with severe aortic stenosis. The study was conducted from January 2012 to June 2014. Preoperative, intraoperative and postoperative parameters were studied in order to investigate the utility of the Perceval S valves in this group of patients. The Perceval S valve implantation seems to be an interesting bio...
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Papers by Nikolaos Baikoussis