Papers by Kristel Marquet
Acta clinica Belgica, 2017
Adverse drug events (ADEs) are a worldwide concern, particularly when leading to a higher level o... more Adverse drug events (ADEs) are a worldwide concern, particularly when leading to a higher level of care. This study defines a higher level of care as an unplanned (re)admission to an intensive care unit or an intervention by a Medical Emergency Team. The objectives are to describe the incidence and preventability of ADEs leading to a higher level of care, to assess the types of drug involved, and to identify the risk factors. A three-stage retrospective review was performed in six Belgian hospitals. Patient records were assessed by a trained clinical team consisting of a nurse, a physician, and a clinical pharmacist. Descriptive statistics, univariate, and multiple logistic regressions were used. In this study, 830 patients were detected for whom a higher level of care had been needed. In 160 (19.3%) cases, an ADE had occurred; 134 (83.8%) of these were categorized as preventable adverse drug events (pADEs). The overall incidence rate of patients transferred to a higher level of car...
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The European journal of general practice, 2017
Multi-morbidity and polypharmacy of the elderly population enhances the probability of elderly in... more Multi-morbidity and polypharmacy of the elderly population enhances the probability of elderly in residential long-term care facilities experiencing inappropriate medication use. The aim is to systematically review literature to assess the prevalence of inappropriate medication use in residential long-term care facilities for the elderly. Databases (MEDLINE, EMBASE) were searched for literature from 2004 to 2016 to identify studies examining inappropriate medication use in residential long-term care facilities for the elderly. Studies were eligible when relying on Beers criteria, STOPP, START, PRISCUS list, ACOVE, BEDNURS or MAI instruments. Inappropriate medication use was defined by the criteria of these seven instruments. Twenty-one studies met inclusion criteria. Seventeen studies relied on a version of Beers criteria with prevalence ranging between 18.5% and 82.6% (median 46.5%) residents experiencing inappropriate medication use. A smaller range, from 21.3% to 63.0% (median 35...
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European Journal of Cardiovascular Nursing, 2004
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European Journal of Cardiovascular Nursing, 2009
The purpose of the study was to assess the profile of adult patients with congenital heart diseas... more The purpose of the study was to assess the profile of adult patients with congenital heart disease who reported a good, moderate, or poor quality of life. We conducted a secondary analysis of data from a large-scale quality-of-life study that included 627 patients. Demographic and clinical variables were retrieved from the medical records and functional status from patient interviews. Overall quality of life was measured using a Linear Analogue Scale. Using K-means cluster analysis, we categorized subjects into a 3-cluster solution: good, moderate, or poor quality of life. Four hundred ninety patients (78.1%) clustered into the good quality-of-life category; 126 patients (20.1%) clustered into the moderate quality-of-life category; and 11 patients (1.8%) clustered into the poor quality-of-life category. Poorer quality of life was associated with lower educational level, unemployment or disability, associated syndromes, instability of the heart disease, and a poorer functional status. Over three-quarters of the patients had a good quality of life, whereas only a small proportion had a poor quality of life. Specific demographic and clinical characteristics associated with a poor quality of life could assists in identifying patients at risk for developing a poor quality of life.
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Eur J Cardiovasc Nurs, 2004
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International Journal of Cardiology, Sep 14, 2007
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Doelstelling: Het in kaart brengen van de opvolging van de parameters op de verpleegafdeling voor... more Doelstelling: Het in kaart brengen van de opvolging van de parameters op de verpleegafdeling voorafgaande aan de ongeplande transfer naar intensieve zorgen. Methodologie: (1) retrospectief dossieronderzoek van alle ongeplande opnames op intensieve zorgen(UIA) in een Limburgs ziekenhuis gedurende 2 maanden (2) UIA omvatten alle patiënten die ongepland opgenomen worden op intensieve zorgen komende van een lager niveau van zorgverlening in het ziekenhuis gedurende dezelfde onderzoeksperiode (3) chirurgische, inwendige, gemengde intensieve zorgen eenheden en cardiac care unit werden geïncludeerd (4) de patiënten werden geselecteerd door de hoofden van de intensieve zorgen eenheden en patiëntveiligheidscoördinator (5) vervolgens werd het patiëntendossier van deze patiënten geanalyseerd naar klinische opvolging van de parameters naar frequentie van registratie en detectie van vroege klinische tekens. Conclusie: (1) de opvolging van parameters is frequenter hoe korter de tijdspanne wordt v...
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Doelstelling: Het in kaart brengen van de klinische indicator "ongeplande opname op intensie... more Doelstelling: Het in kaart brengen van de klinische indicator "ongeplande opname op intensieve zorgen" door middel van een dossieronderzoek. Methodologie: (1) retrospectief dossieronderzoek van alle ongeplande opnames op intensieve zorgen in een Limburgs ziekenhuis gedurende twee maanden (2) chirurgische, inwendige, gemengde intensieve zorgen eenheden en cardiac care unit werden geïncludeerd (3) de ongeplande opnames werden geselecteerd door de hoofden van de intensieve zorgen eenheden en patiëntveiligheidscoördinator (4) vervolgens werd het patiëntendossier van deze patiënten geanalyseerd naar demografische, klinische en outcome parameters (5) een anesthesist beoordeelde aan de hand van het dossier de American Society of Anesthesiologists(ASA)score Conclusie: (1) 13,9% van de opnames op intensieve zorgen zijn ongepland (2) deze patiënten hebben veel verzorging nodig, toch overlijdt bijna 1 op 3 patiënten binnen 3 maanden. Het is daarom belangrijk het zorgverloop van deze ...
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B-ENT
Research shows that 51.4% of adverse events in hospitals occur in surgery and that 3-22% of surgi... more Research shows that 51.4% of adverse events in hospitals occur in surgery and that 3-22% of surgical patients experience adverse events. The risk may be even higher when turnover is high and when patients are children, as is often the case in ear, nose and throat surgery. This quality project therefore started in response to requests from physicians in two hospitals in the Flemish part of Belgium. The aim of this study is to use the Healthcare Failure Mode & Effect Analysis method to evaluate the process flow for ear, nose and throat patients, and to redesign the process to enhance patient safety. In two One Day Clinics, processes were prospectively analysed using the Healthcare Failure Mode & Effect Analysis method. Similar potential failures were reported in both hospitals. The major failure mode was linked to the absence of an active identity check throughout the process. The process was therefore redesigned by implementing a surgical safety checklist and an active identity check...
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Health and quality of life outcomes, Jan 28, 2004
The 'Schedule for the Evaluation of Individual Quality of Life-Direct Weighting' (SEIQoL-... more The 'Schedule for the Evaluation of Individual Quality of Life-Direct Weighting' (SEIQoL-DW) is an instrument developed to measure individual quality of life. Although this instrument has been used in numerous studies, data on validity and reliability are sparse. This study aimed to examine aspects of validity, reliability and responsiveness of the SEIQoL-DW on data obtained in adults with congenital heart disease, by using the new standards of psychological testing. We evaluated validity evidence based on test content, internal structure, and relations to other variables, as well as the stability and responsiveness of the SEIQoL-DW. Evidence was provided by both theoretical considerations and empirical data. Empirical data were acquired from two studies. Firstly, using a cross-sectional study design, we included 629 patients with congenital heart disease. Secondly, 130 of the 629 initially included patients readministered the questionnaires approximately one year after the ...
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BMC research notes, Jan 16, 2014
An accurate medication overview is essential to reduce medication errors. Therefore, it is essent... more An accurate medication overview is essential to reduce medication errors. Therefore, it is essential to keep the medication overview up-to-date and to exchange healthcare information between healthcare professionals and patients. Digitally shared information yields possibilities to improve communication. However, implementing a digitally shared medication overview is challenging. This articles describes the development process of a secured, electronic platform designed for exchanging medication information as executed in a pilot study in Belgium, called "Vitalink". The goal of "Vitalink" is to improve the exchange of medication information between professionals working in healthcare and patients in order to achieve a more efficient cooperation and better quality of care. Healthcare professionals of primary and secondary health care and patients of four Belgian regions participated in the project. In each region project groups coordinated implementation and report...
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Critical Care Medicine, 2015
The objectives of this study are to determine the prevalence and preventability of adverse events... more The objectives of this study are to determine the prevalence and preventability of adverse events requiring an unplanned higher level of care, defined as an unplanned transfer to the ICU or an in-hospital medical emergency team intervention, and to assess the type and the level of harm of each adverse event. A three-stage retrospective review process of screening, record review, and consensus judgment was performed. Six Belgian acute hospitals. During a 6-month period, all patients with an unplanned need for a higher level of care were selected. The records 6-month period, the records of all patients with an unplanned need for a higher level of care were assessed by a trained clinical team consisting of a research nurse, a physician, and a clinical pharmacist. Adverse events were found in 465 of the 830 reviewed patient records (56%). Of these, 215 (46%) were highly preventable. The overall incidence rate of patients being transferred to a higher level of care involving an adverse event was 117.6 (95% CI, 106.9-128.3) per 100,000 patient days at risk, of which 54.4 (95% CI, 47.15-61.65) per 100,000 patient days at risk involving a highly preventable adverse event. This means that 25.9% of all unplanned transfers to a higher level of care were associated with a highly preventable adverse event. The adverse events were mainly associated with drug therapy (25.6%), surgery (23.7%), diagnosis (12.4%), and system issues (12.4%). The level of harm varied from temporary harm (55.7%) to long-term or permanent impairment (19.1%) and death (25.2%). Although the direct causality is often hard to prove, it is reasonable to consider these adverse events as a contributing factor. Adverse events were found in 56% of the reviewed records, of which almost half were considered highly preventable. This means that one fourth of all unplanned transfers to a higher level of care were associated with a highly preventable adverse event.
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Critical Care, 2015
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European Journal of Cardiovascular Nursing - EUR J CARDIOVASC NURS, 2004
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Papers by Kristel Marquet