Chemistry:Bencyclane
From HandWiki
Names | |
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IUPAC name
3-[(1-benzylcycloheptyl)oxy]-N,N-dimethylpropan-1-amine
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Identifiers | |
3D model (JSmol)
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ChEMBL | |
ChemSpider | |
PubChem CID
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UNII | |
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Properties | |
C19H31NO | |
Molar mass | 289.45554 |
Pharmacology | |
1=ATC code }} | C04AX11 (WHO) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
Infobox references | |
Bencyclane is an antispasmodic, vasodilator, and platelet aggregation inhibitor.[1]
Synthesis
Grignard addition of benzylmagnesiumbromide to suberone would give 1-benzylcycloheptanol [4006-73-9] (1'). Williamson ether synthesis with 3-dimethylaminopropylchloride [109-54-6] (2) completed the synthesis of bencyclane (3).
See also
References
- ↑ J. Elks, ed (2014). The Dictionary of Drugs: Chemical Data, Structures and Bibliographies. Springer. https://books.google.com/books?isbn=1475720858.
- ↑ Pallos, L.; Budai, Z.; Zólyomi, G. (1972). "Basic ethers of 1-substituted cycloalkanols. 1.". Arzneimittel-Forschung 22 (9): 1502–1505. PMID 4678613.
- ↑ Pallos, L.; Budai, Z.; Zólyomi, G. (1972). "Basic ethers of 1-substituted cycloalkanols. 2.". Arzneimittel-Forschung 22 (9): 1505–1509. PMID 4678614.
- ↑ Anon., ES patent 376120 (1972-04-01 to Gallardo Antonio SA).
- ↑ Spaeter Genannt Werden Wird, DE patent 2455051A1 (1975 to Andreu S A Lab).
Original source: https://en.wikipedia.org/wiki/Bencyclane.
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