Primer3Plus requires Primer3, please intall first:

https://github.com/primer3-org/primer3

git clone https://github.com/primer3-org/primer3plus.git

cd primer3plus

The server runs in a terminal

Install the dependencies:

sudo apt install python3 python3-flask python3-flask-cors npm

Start the server:

cd PATH_TO_PRIMER3PLUS/primer3plus

export PATH=$PATH:/PATH_TO_PRIMER3/src

echo $PATH

python server/server.py

The client requires a different terminal

Install the dependencies:

cd PATH_TO_PRIMER3PLUS/primer3plus/client

npm install

Start the client:

cd PATH_TO_PRIMER3PLUS/primer3plus/client

npm run dev