The easiest way to install the latest version is by using pip/easy_install to pull it from PyPI:

pip install tweepy

You may also use Git to clone the repository from Github and install it manually:

git clone https://github.com/tweepy/tweepy.git
cd tweepy
python setup.py install

Python 2.6 and 2.7, 3.3, 3.4 & 3.5 are supported.